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Exposure to air pollution associated with asthma, wheezing attacks in children

 


August 20, 2020

Duration: 2 minutes

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Disclosure: Holst has not reported any related financial disclosures. See the survey for relevant financial information for all other authors.

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Children exposed to higher levels of air pollution are at an increased risk of developing asthma and persistent wheezing compared to unexposed children. of BMJ..

“Whether the onset of asthma and persistent wheezing are associated with family-related factors, High levels of air pollution In children’s residential areas, it was associated with an increased risk of asthma and persistent wheezing and whether the association between air pollution and asthma and persistent wheezing differed by family-related factors. ” Gitte J. Holst, MD, doctor student Written by a colleague in the Environmental, Occupational and Health section of Aarhus University in Denmark.

Child using an asthma inhaler
Source: Adobe Stock.

The researchers conducted a national case-control study of 3,192,785 Danish children born between 1997 and 2014. Asthma and persistent wheezing Development from 1 to 15 years. Exposures to air pollution assessments were obtained from the Danish Air Pollution Modeling System and data on parental asthma were obtained from the Danish National Patient Registry. The researchers evaluated the mother’s smoking status at the first meeting during pregnancy, parental education from the education record, and parental income from the income record.

Children with asthma parents (adjusted HR = 2.29; 95% CI, 2.22-2.35) and mothers who smoked during pregnancy (aHR = 1.2; 95% CI, 1.18-1.22) had an asthma incidence. it was high. Parents with high education (aHR = 0.72; 95% CI, 0.69-0.75) and high income (aHR = 0.85; 95% CI, 0.81-0.89) had a lower incidence of asthma.

Exposure to particulate matter 2.5 g or less (HR per 5 g / mThree = 1.05; 95% CI, 1.03-1.07) 10 g or less (HR per 5 g / m)Three = 1.04; 95% CI, 1.02-1.06) and nitrogen dioxide (HR per 5 g / m)Three = 1.04; 95% CI, 1.03-1.04) was associated with an increased risk of asthma and persistent wheezing.

The positive association of particulate matter up to 2.5 g was consistent between different models.

“The findings of this study strengthen the evidence that pregnant asthma, parental education, and mother’s smoking are risk factors for developing asthma and persistent wheezing in children.” High level [particulate matter 2.5 g or less] It was more likely to develop asthma and persist wheezing,” the researchers say. “Thus, these findings support new evidence that exposure to air pollution may affect the development of asthma. This finding needs to be substantiated in future studies. .”

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