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Study: Estrogen Alleviates Symptoms of Severe Covid-19 Infection in Women

 


New research suggests that estrogen may help reduce the severity of COVID-19 infection in women. Research suggests that this may be the reason why men are more likely to be infected with the COVID-19 virus than women. Estrogens are female sex hormones involved in female sexual and reproductive development.

The research was published in the journal Current Hightension Reports. In this study, the research team reviewed preclinical data published on the activity of estrogen hormones.

Leanne Groban, lead author of the Wake Forest Baptist Health Center in the United States, said: “.

After reviewing published data, the researchers found that angiotensin converting enzyme 2 (ACE2) is the cellular receptor for the Covid-19 virus. ACE2 attaches to the heart, arteries, kidneys, and intestines and helps deliver coronavirus to cells in these organs.

Estrogen helps lower the level of ACE2 in the heart and helps prevent the severity of Covid-19 infection in women. Conversely, elevated levels of ACE2 in tissues can exacerbate the symptoms of Covid-19 infection. According to another recent study published in the European Heart Journal, men have higher levels of ACE2 in their blood than women. And this is why men are more likely to experience severe symptoms of coronavirus infection than women.

However, Covid-19-related deaths in men can be due to many reasons, including differences in lifestyle and body innate immunity.

According to Groban, “Our review of the role of estrogen hormones in the expression and regulation of ACE2 explains gender differences in Covid-19 infection and outcome, and guides current treatments and the development of new treatments. I hope.”

The study authors commented, “In summary, the accumulated evidence of a rather low rate of Covid-19 disease severity in women needs to be further investigated.”

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