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Intestinal fungi associated with higher risk of Alzheimer’s disease can be reduced by a ketogenic diet

 


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Researchers at the Wake Forest School of Medicine found that certain fungi in the intestines found in people with mild cognitive impairment (MCI) were at high risk for Alzheimer’s disease and could benefit from eating a modified Mediterranean diet. I found that you can change it.

A small study is published in the current online version of the journal EBioMedicine..

“Our research shows that the unique fungi that are symbiotic with bacteria in the intestines of MCI patients can be regulated through the Mediterranean ketogenic diet,” said Wake Forest School of Medical, part of Wake. Hariom Yadav, associate professor of molecular medicine at Forest Baptist Health.

In a single-center, randomized, double-blind, crossover pilot study, Yadav’s team Sequencing the fungal rRNA ITS1 gene with 17 (11 diagnosed with MCI, 6 diagnosed with normal dementia) A modified Mediterranean ketone diet or American Heart Association to determine the correlation between cerebrospinal fluid and Alzheimer’s markers of enterobacteria Before and after 6 weeks of dietary intervention.

“We don’t fully understand how these fungi contribute to Alzheimer’s disease, but this is the first study of its kind to reveal their role in our mental health. Alzheimer’s Disease To”. “It’s also It can reduce harmful fungi in the gut, such as eating a ketogenic diet, and may help reduce the process of Alzheimer’s disease in the brain. ”


Dietary effects on intestinal bacteria may play a role in reducing the risk of Alzheimer’s disease


For more information:
Ravinder Nagpal et al. Interaction of intestinal mycobiome with diet, enterobacteria, and Alzheimer’s disease markers in subjects with mild cognitive impairment: a pilot study EBioMedicine (2020). DOI: 10.1016 / j.ebiom.2020.102950

Quote: An intestinal fungus at high risk for Alzheimer’s disease has been available at https://medicalxpress.com/news/2020-08-fungi-gut-linked-higher-alzheimer since August 31, 2020. html

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