Health
Along with several other factors such as early onset, combined oral contraceptives, and premature menopause-ScienceDaily
Comprehensive (Umbrella) analysis of data published by that pregnancy complications such as miscarriage, pre-eclampsia, gestational diabetes (gestational diabetes), and preterm birth are associated with an increased risk of heart disease in later years. Is suggested BMJ today.
Several other factors associated with fertility and pregnancy also appear to be associated with subsequent cardiovascular disease, researchers say, early onset period, use of combined oral contraceptives, polycystic ovary. It is said to include syndrome and premature menopause.
However, longer periods of breastfeeding reduce the risk of cardiovascular disease.
Previous studies have suggested that risk factors specific to women may be associated with cardiovascular disease and stroke, but how the quality of evidence and findings apply to public health and clinical practice. There is a lack of clarity as to whether it can be converted to.
Therefore, a team of British researchers searched relevant research databases for published systematic reviews and meta-analyses investigating the association between reproductive factors in women of reproductive age and the risk of subsequent cardiovascular disease. I searched.
A total of 32 reviews were included, assessing multiple risk factors over an average follow-up of 7-10 years.
Researchers have found that early onset (early menstruation), combined oral contraceptive use, polycystic ovary syndrome, miscarriage, stillbirth, preeclampsia, diabetes during pregnancy, preterm birth, low birth weight, and premature menopause. Several factors were found, including up to twice the risk of cardiovascular outcomes.
Pre-eclampsia was associated with a four-fold risk of heart failure.
Possible explanations for these associations include family medical history, genetics, weight, hypertension and cholesterol levels, and chemical imbalances due to the use of hormonal contraceptives.
However, no association was found between cardiovascular outcomes and current use of progesterone-only contraceptives, use of parenteral hormone contraceptives, or fertility treatment.
In addition, breastfeeding was associated with a reduced risk of cardiovascular disease.
Researchers have pointed out some limitations, such as the fact that missing data and reviews are primarily based on observational evidence, which may have been influenced by other unmeasured (confounding) factors. Gender cannot be ruled out.
Nonetheless, they say the evidence reported in this comprehensive review suggests that women’s reproductive profile is associated with a future risk of cardiovascular disease from initial tide to menopause. I will.
They conclude that they provide recommendations that can be incorporated into guidelines, such as clarifying the quality of evidence, identifying gaps between evidence and practice, and incorporating reproductive risk factors as part of the risk assessment of cardiovascular disease. ..
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