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Metformin, a type 2 diabetes drug recalled for possible contamination with carcinogens

Metformin, a type 2 diabetes drug recalled for possible contamination with carcinogens

 


Two lots of the widely used type 2 diabetes drug, metformin, have been recalled because they can be contaminated with compounds that can cause cancer. Metformin is designed to lower blood sugar levels.

Our Institute Co., Ltd.Based in Kansas City, Missouri, announced on Monday that it would voluntarily recover 750 mg of metformin HCl sustained-release tablets USP. A recall posted by the US Food and Drug Administration.

By test Nitrosamine, or NDMA, Exceeds the acceptable limit for recalled tablets.

The chemical NDMA is considered to be carcinogenic. US Environmental Protection Agency. It is an organic chemical used in the production of liquid rocket fuels and can be a by-product of manufacturing, including pharmaceutical manufacturing. It is also found in foods such as water, meat, dairy products and vegetables.

NDMA is also found in certain blood pressure and antacids.

This is the latest A series of metformin recalls It is associated with potentially cancer-causing contaminants in drugs.

Nostram said he had not received any reports of adverse events related to the recall. The company also notified its distributors and said it was arranging for the recalled products to be returned.

Affected products are packaged in 100 HDPE bottles under NDC29033-056-01. Affected metformin HCl sustained release tablets, USP 750 mg lots are NDC 29033-056-01, lot numbers MET200101 and MET200301, with an expiration date of 05/2022. It can be identified as an off-white rectangular tablet debossed with “NM7”.

More than 34 million people in the United States have diabetes (about 1 in 10), of whom about 90-95% are diagnosed with type 2 diabetes. Centers for Disease Control and Prevention.

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