Tests that use earwax to measure cortisol levels “could transform the diagnosis and take care of millions of people. depression“, According to the results of a small study.
Research results published in the journal helix, Earwax samples have been found to contain more stress hormones than hair samples and can provide a more accurate method for measuring chronic cortisol levels.
Earwax samples are less likely to be affected by confounding factors such as short-term stressful events and alcohol consumption, the researchers said.
“Sampling cortisol is notorious for being very difficult because hormone levels can fluctuate, so the sample may not accurately reflect a person’s chronic cortisol levels,” he said. Dr. Andres Herane-Vives of the Institute of Cognitive Neuroscience at University College London explained. Survey.
“In addition, the sampling method itself can induce stress and affect results,” he added.
The device can be used at home
Dr. Herane-Vives has developed an earwax sampling device that can be used at home without clinical supervision.
The researchers invited 37 participants to test various cortisol sampling techniques.
Earwax in both ears was extracted using standard syringe procedures commonly associated with local pain.
One month later, the earwax of the left ear was collected by the same procedure.
On the other hand, a sample of earwax from the right ear was taken by the participants themselves using the new device.
The researchers also analyzed hair samples representing previous month’s cortisol output and serum samples that reflected the effect of systemic stressors on cortisol levels.
The study found that self-sampling devices did not locally increase cortisol. We also provided cortisol levels that are least likely to be affected by confounding factors last month.
“Accurate and affordable”
The authors stated that self-obtained earwax samples may provide an alternative, accurate, but more affordable method for measuring chronic cortisol levels.
Dr. Herane-Vives said earwax has properties similar to the honeycomb of another natural wax, the bee honeycomb, which is known for its antiseptic properties and resistance to bacterial contamination. These properties make it suitable for home sampling, have a low risk of contamination, and can be sent for laboratory analysis.
Dr. Herane-Vives said: Cushing’s syndrome, And potentially many other conditions. “
Researchers said the test could be used to measure blood sugar levels that accumulate in earwax, and potentially COVID-19 antibodies.
Dr. Heran Vibes founded the company, treasureBring your device to market with funding from UCL Hatchery Startup Incubator..
Measurement of earwax cortisol concentration using non-stress sampling method. Helyon. Release November 4, 2020.
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