Early trials of the Synovac vaccine have shown that it provokes an immune response: Coronavirus UpdateExBulletin

Sinovac has released data on early clinical trials of vaccines against coronavirus.

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Jakub Porzycki / NurPhoto via Getty Images

Sinovac has released data on early clinical trials of vaccines against coronavirus.

Jakub Porzycki / NurPhoto via Getty Images

As companies around the world compete for the development of coronavirus vaccines Hundreds of thousands of people have been vaccinated in China With a vaccine before its effectiveness is proven in trials. Currently, researchers have published preliminary results showing that the vaccine provokes an immune response, but it’s too early to say whether it can prevent the disease.

The· result It was published in a peer-reviewed paper in the medical journal The Lancet on Tuesday. The data are from the earliest clinical trials (Phase 1 and 2) of a vaccine called Corona Vac.

Early trials tested whether the vaccine evoked an immune response and also monitored side effects using two different doses and vaccine schedules.

Phase 1 and 2 trials are not designed to demonstrate efficacy, he said. Dr. Kirsten Like, Immunologist and Professor of Medicine, University of Maryland School of Medicine.

“This is not a Phase 3 study that can be said to be effective or 90% protected. We don’t know,” she adds.

CoronaVac uses inactivated coronavirus, which makes it different from the mRNA or messenger RNA vaccines produced by Pfizer and Moderna. CoronaVac was manufactured in a proven way, but with new mRNA technology Until now, no mRNA vaccine has been approved by the Food and Drug Administration...

Researchers say the latest Corona Vac results are helping them move on to Phase 3 trials.

They found that the Sinovac vaccine evoked an antibody immune response, but at lower levels than those found in people who recovered from the coronavirus. By comparison, Moderna and Pfizer Reported the same or better Antibody levels of mRNA vaccine than those who recovered.

“I would be worried … it [CoronaVac] It induced lower antibody levels than those seen with other vaccines and appeared to be lower than those found in most people who recovered from the disease. ” Dr. Gregory Poland, Vaccine scholar and professor at the Mayo Clinic in Rochester, Minnesota.

Indonesia, Turkey and Brazil are currently in Phase 3 trials of Corona Vac. There are tens of thousands of participants.Indonesia I’m reportedly aiming Deploy the vaccine by the end of the year.

modern Said on monday The vaccine is 94.5% effective in preventing disease, Pfizer Announced on Wednesday Its effectiveness rate is 95%. Pfizer is ready to seek approval from the US Food and Drug Administration for emergency use of the vaccine.

One of the potential benefits of CoronaVac is that it’s cheap and quick to create. Poland states that it may be useful in regions of the world where other vaccines may not be available, even though it provides only partial protection compared to mRNA vaccines.

“… Indonesia, part of China … would be very logistically very difficult to transport [an mRNA] Vaccines at the required low and ultra-low temperatures. But nevertheless, the more vaccines there are worldwide, the better, assuming they are safe and effective, “he added.

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