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Kidney Disease Leading COVID-Related Hospitalization Risk Factors: Study Reveals | Health News
Washington: Analysis of Geisinger’s electronic health records reveals that chronic kidney disease is a major risk factor for hospitalization. COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears..
From March 7th to May 19th, a team of Gaisinger researchers investigated the health records of 12,971 people tested for COVID-19 within the Gaizinger system. Of this group, 1,604 were COVID positive and 354 required hospitalization. The team analyzed records of specific clinical conditions, including renal, cardiovascular, respiratory, and metabolic conditions, associated with COVID-19 hospitalization.
Overall, chronic kidney disease was most strongly associated with hospitalization, with COVID-19 patients with end-stage renal disease 11 times more likely to be hospitalized than patients without renal disease. The results were published in PLOS ONE.
“Previous studies have identified a variety of health conditions associated with an increased risk of COVID-related hospitalization, including diabetes, heart failure, hypertension, and chronic kidney disease. What is important here is the magnitude of kidney disease-related risk. “These findings are COVID-19-related illnesses in patients with kidney disease and other high-risk conditions,” said Alex Chan, a nephrologist and co-director of the Gaisinger Kidney Health Institute. It highlights the need to prevent. ” ..
It is not yet completely clear how the underlying medical condition increases the risk of COVID-19-related complications. However, the study found that the physiological stress caused by an excessive inflammatory response to COVID-19 infection could destabilize organs already weakened by chronic disease, or that viral organ damage was these. It suggests that it may act as a “second hit” to the organ. With this hypothesis, the kidneys and heart are one of the tissues with the highest expression of the SARS-CoV-2 receptor, ACE2, “the team writes.
Although the sample size surveyed was relatively small, Geisinger’s resources as an integrative medicine system provided a fairly comprehensive analysis of the available data. Our team used extensive electronic medical records, unique demographic data, and a new approach made possible by integrative medicine. Dr. Tooraj Mirshahi, an associate professor of the Department of Molecular Function and Genome at Geisinger, said: “We were able to carry out this study despite the much smaller number of COVID-19 cases compared to large hospitals in metropolitan areas,” Mirshahi added. ..
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