Health
Studies show that plasma reduces the risk of severe Covid-19 when given early
“It will be difficult to find and diagnose them in that fading little window,” said Dr. Iran Schwartz, an infectious disease specialist at the University of Alberta who was not involved in the study. “This study looks solid, but it’s not always practical in the real world.”
Dr. Titanji of Emory University said plasma has additional logistical hurdles. Treatment is given as an intravenous infusion (a process that requires a skilled hand), and the patient should then be monitored. It may be easy in a long-term care facility, but she said it is much harder to achieve for the general public.
Also, plasma may not work as well as monoclonal antibody therapy. This is a synthetic formulation that focuses on one or two types of antibodies at a time, rather than the entire slew produced in large quantities in the laboratory, rather than taken from human blood. Immune system By naturally. Two types of monoclonal antibody treatment Emergency use in Covid patients is permitted.
However, plasma has several advantages over monoclonal antibody treatment, Dr. Pollack pointed out.
Because monoclonal antibodies are synthetic and cumbersome to manufacture Expensive price tag, Sometimes costs thousands of dollars (The US government I paid some doses in advance).Limited supply chain of treatment, and Unexpectedly low demandKeeping it out of the reach of many patients in need, in the United States and abroad.
In countries like Argentina, plasma may be one of the best treatment options available, Dr. Polack said. Plasma infusions in Buenos Aires cost less than $ 200 per patient, he said. “It’s more accessible, cheaper, and more universal,” he said.
Even in the United States, Dr. Wang of Stanford University said plasma is “the only game in a town that is widely available from an antibody therapy perspective.”
Rather than seeing monoclonal antibodies as an upgrade to convalescent plasma, “they are each in different locations within the arsenal,” Dr. Pilovsky said. “Everything that has the ability to control this virus is a truly incredible advantage at this time.”
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