COVID-related pneumonia is much more difficult to treat — this is how NU researchers want us to be able to fight it.

Researchers at Northwestern University say they have potentially found a more effective way to treat the life-threatening condition of the virus, COVID-related pneumonia.

The peer-reviewed study was published online in a scientific journal on Monday. Nature.. A small, early-stage human study using data from Northwestern University will take weeks to see if drug treatment can significantly reduce the effects of pneumonia on people hospitalized with the virus. Expected to start within.

Although it is unlikely that treatments will be developed before mass vaccination essentially controls the pandemic, doctors expect people to continue to get sick. In fact, if a similar virus emerges in the future, treatment can be very necessary.

“There is no doubt that these associated coronaviruses will increase further,” Scott Budinger, director of lung and emergency medicine at Northwestern University’s Fineberg School of Medicine, said in an interview. “I think we are better prepared.”

According to Budinger, even if vaccinated, it is unlikely that 100% will be vaccinated, so COVID-19 will continue to make people sick.

Nearly 375,000 people have died and more than 22 million cases have been reported in the United States.

According to Budinger, Northwestern University researchers are investigating unconfirmed pharmaceuticals within the next few weeks for the first-stage study of the three clinical trials normally required for approval of treatment by the U.S. Food and Drug Administration. It may start working with the company.In addition, Northwestern University is conducting government-funded research Published online As a result, any pharmaceutical company can consider testing possible treatments.

“I hope some pharmaceutical companies are looking at the data, not just here in the northwest, but elsewhere in the country, and think their drugs may help,” Budinger said. I will.

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Budinger and his colleagues have been studying pneumonia for about 10 years. They focused their research on COVID-related pneumonia early last year. Scientists have studied genetic material in fluid samples taken from critically ill patients to help understand the route of the virus to pneumonia.

They found the virus spreading slowly in the lungs and explained why COVID patients tend to suffer from pneumonia for a much longer period of time. It takes an average of 14 days in the intensive care unit of a hospital, compared to about 4 days of pneumonia caused by influenza. The type of illness.

“Their illness lasted for a long time,” Budinger said. “That’s why COVID-19 puts such a burden on our healthcare system.”

According to Budinger, drugs can prevent the virus from attacking certain white blood cells, thereby reducing the effects of the disease on the more common symptoms of influenza and thus preventing severe pneumonia. I will.

“The best way to combat a pandemic is to get a vaccine that always works. There seems to be some great news,” Bajinga said of emergency use or development vaccines. “The second way to combat this disease is to change from severe to mild.”

Brett Chase’s environmental and public health reports were made possible with a grant from the Chicago Community Trust.

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