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Scientists identify three types of COVID-19 patients based on clinical outcome

Scientists identify three types of COVID-19 patients based on clinical outcome

 


The categories — Phenotype I. Phenotype II and Phenotype III — are based on the patient’s comorbidities, complications, and clinical outcomes.

Scientists identify three types of COVID-19 patients based on clinical outcome

There is little evidence that surface infections are a common way for coronaviruses to spread. The main way it spreads is by air, either by large droplets due to close contact or by small droplets called aerosols.

Scientists have identified three different types COVID-19 (new coronavirus infection) Depending on comorbidities, complications, and clinical outcomes, the patient’s disease characteristics are advances that may help target future interventions to the highest-risk individuals.New research published in the journal PLOS ONEWe analyzed electronic health records (EHRs) from 14 hospitals in the Midwestern United States and 60 primary care clinics in Minnesota.The study included 7,538 confirmed patients, according to researchers, including researchers at the University of Minnesota in the United States. COVID-19 (new coronavirus infection) Between March 7 and August 25, 2020, 1,022 patients required hospitalization.

Nearly 60% of the patients included in the study presented what the researchers called “phenotype II.”

They said that about 23 percent of patients exhibited “phenotype I” or “harmful phenotype,” which was associated with the worst clinical outcome. The researchers said these patients had the highest levels of comorbidities associated with heart and kidney dysfunction.

According to this study, 173 patients (16.9%) showed “phenotype III” or “favorable phenotype,” and scientists said this was associated with the best clinical outcome. Although this group had the lowest complication and mortality rates, scientists found that these patients had the highest incidence of respiratory complications compared to other phenotypes and a 10 percent risk of readmission. Said it was expensive.

Overall, they said that phenotypes I and II were associated with a 7.30-fold and 2.57-fold increased risk of death compared to phenotype III.

Based on the results, scientists said that such phenotypic-specific medicine could be improved. COVID-19 (new coronavirus infection) result.

However, they believe that further research is needed to determine the usefulness of these findings in clinical practice.

“Patient is not suffering COVID-19 (new coronavirus infection) With a uniform problem. Identifying similarly affected groups not only provides a better understanding of the disease process, but also accurately directs future interventions to the most at-risk patients, “scientists added.

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