Health

Research Results Link Breast Cancer in Men to Male Infertility

Further sensitivity analysis to control family alcohol consumption, family history, liver disease, and smoking does not find compelling evidence that these factors influenced results.

Risk Invasive breast cancer in men According to the results of a study published in, it may be related to infertility Breast cancer research..

Researchers at the Cancer Institute in London, UK, interviewed a man diagnosed in 1998 in the UK and Wales. Breast cancer, 383, or about 19.2%, saying that they have no children, 112, or about 5.6%, self-reported infertility. All men included were under the age of 80 and were diagnosed with breast cancer between 2005 and 2017.

In addition, we compared individuals with 1597 men in the unrelated control group. About 5% of men in the control group reported infertility.

The researchers aimed to investigate the potential relationship between childlessness and self-reported infertility and breast cancer risk in men.

The researchers concluded that the risk of invasive breast cancer tumors was significantly associated with male infertility.

It is based on a comparison of 47 individuals with breast cancer and 22 men in the control group who do not have cancer but have self-reported infertility.

In addition, researchers did not find a link between the risk of breast cancer and partner infertility, or when the cause of infertility is unknown.

After further investigation, the researchers observed a higher number of men with breast cancer, 383-174 each, compared to men in the control group.

However, due to the range of cultural and social reasons for choosing not to have children, having no children does not fully reflect male infertility, the researchers said.

Based on 160 individuals with non-invasive breast cancer tumors, which are cancerous cells that do not spread beyond the place where they were originally formed, compared to 1597 controls, of breast cancer and childless or infertility. The associated risk was not significant.

Researchers conducted further sensitivity analyzes to manage the family history of alcohol consumption, breast cancer, liver disease, and smoking, but found no strong evidence that these factors affected the results. .. However, the researchers did not control obesity, but one of the analyzes from 11 men with Klinefelter’s syndrome, 9 men with previous cancer, 29 men with severe obesity, and 169 men with testicular disease. Excluded part data.

In addition, the three born as women were not included in the analysis.

Researchers said self-reported infertility could be misclassified, adding that examining infertility in medical records could reduce further research bias.

“The cause of breast cancer in men is largely unknown, partly because it is rare and partly because previous studies were small. The evidence presented in our study is infertility. Further studies need to confirm the association between breast cancer and breast cancer, suggesting that future research is needed on potential underlying factors such as hormonal imbalances with the Cancer Institute’s Genetics. Epidemiology stated in a statement.

reference

The risk of breast cancer in men may be associated with infertility in men. Eurek Alert. news release. May 16, 2022. Accessed on May 18, 2022. https: //www.eurekalert.org/news-releases/952532

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Research Results Link Breast Cancer in Men to Male Infertility