The price of new drugs is soaring. Can the law stop it?

The New drug price It has risen for more than a decade in the United States, according to a study published Tuesday.

According to the research letter Journal of American Medical AssociationThe launch price of new brand drugs increased by nearly 11% every year from 2008 to 2021.

“These prices are much higher than other healthcare services,” said Dr. Benjamin Roma, lead author and researcher on regulatory, treatment and legal programs at Brigham and Women’s Hospital in Boston. I am.

Rome, along with his colleagues, observed price increases for all types of medicines, including: Anti-cancer agentNon-cancer drugs, tablets, injections, he said.

“Ultimately, all medical costs are paid by the consumer. Either direct out-of-pocket costs, higher premiums, or taxes in the case of public health insurance.” “Insurers are expensive. We may require pre-approval of a new drug or may not cover the drug at all, “he added.

In the study, researchers calculated the negotiable sticker price, or net price, of new drugs on the market. These prices were adjusted for inflation and calculated taking into account the rebates that many pharmaceutical companies offer to their medicines.Due to their analysis, researchers also found that many of the new drugs launched during the study period Rare diseases and biological therapies...

Researchers limited the scope to drugs sold by public companies, with an average net price of nearly 400 new drugs in total.

The median annual supply of drug prices rose from $ 2,115 in 2008 to over $ 180,000 in 2021. The biggest rise was in anti-cancer drugs and treatments used to treat rare illnesses. In 2008, 9% of medicines cost more than $ 150,000 a year, compared to 47% in 2021.

They found that 65% of new drugs contain new active ingredients that are not yet available in the United States. Twenty-five percent were biologics, which were higher cost polymers than previous small molecule drugs, and 22% were cancer treatments.

Prices have risen regardless of drug type, Rome said, adding that it is unclear whether the newly developed drug is superior to the old available options.

“Previous studies have shown that only about one-third of new drugs demonstrate substantial benefits over existing treatments,” he said.

Researchers didn’t see how the price changed after the initial launch price. However, according to Rome, new drugs usually exist on the market for an average of 12 to 17 years without competition from generic drugs, ultimately lowering the price of branded drugs. According to the authors of the study, pharmaceutical companies will raise prices on a regular basis without competition.

According to Karen Van Nice, a research assistant professor at the Schaefer Center for Health Policy and Economics, University of Southern California, pharmaceutical companies “set prices high because they are protected.”

Van Nuys, who was not involved in the new study, said the largest price increases were seen in 2020 and 2021. Half of the new drugs entering the market cost more than $ 150,000 a year in 2020 and 2021, but the rise in 2021 was mainly driven by the cost of $ 1.6 million and $ 3.2 million a year. Due to two new cancer drugs.

She believes the significant rise was caused by the possibility of federal regulation of rising drug prices.

In 2021, Congress was discussing a law aimed at curbing drug price increases, which could have had unintended consequences, Van Nuys said.Clauses that are part of the Biden administration’s impasse Regain better behaviorIf drug prices rise above inflation, pharmaceutical companies will have to pay Medicare a rebate.

“You can launch at any price you like, but once you launch you can’t go above inflation and raise the price,” she said. “For manufacturers who may face such restrictions after launch, we will raise the list price.”

“It’s still raising drug prices, it only changes the way or mechanism of raising prices,” Vannize said.

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