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CDC Panel Supports Novavax COVID Vaccine for Adults

CDC Panel Supports Novavax COVID Vaccine for Adults

 


The CDC’s Advisory Committee on Immunization Implementation (ACIP) has unanimously approved the recommendation of the Novavax COVID-19 vaccine to individuals over the age of 18.

The advisory board voted 12-0 to approve a two-dose primary series of co-protein-based vaccines given at 3-week intervals.The recommendation is from the FDA Emergency use authorization last week.

Shortly after the meeting, the ACIP recommendations were approved by CDC Directors Rochelle Walensky, MD and MPH.

Ongoing randomized trials in the United States and Mexico proved that this shot was safe and effective in preventing mild, moderate, and severe illnesses, so recommendations were expected. ..

Oliver Brookes, MD, MD, ACIP member, Chief Medical Officer of Watts Healthcare in Los Angeles, said: “Perhaps in the hope that this protein subunit vaccine will change from unvaccinated to vaccinated, we really need to focus on that population.”

CDC experts pointed out that there are differences in vaccine coverage between young patients and those from ethnic and ethnic backgrounds, and they are less likely to be immunized against COVID-19. In addition, people without health insurance or primary care providers are less likely to be vaccinated with COVID.

“As always, vaccination of unvaccinated individuals remains a top priority,” said CDC’s Evelyn Twentyman, MD, MPH. “The first COVID-19 vaccine, utilizing traditional and longer-standing vaccine technology, offers additional options for unvaccinated people.”

Nonetheless, some ACIP members expressed concern about the uncertainty of the Novavax booster dose timeline and the confusion over vaccine labeling.

According to the manufacturer, the Novavax COVID vaccine showed 93% efficacy against the variant of concern and the mutant of concern, but initially high, as seen with other COVID-19 vaccines. The antibody titer decreased after 6 months.

Pablo Sanchez, MD, an ACIP member of The Ohio State University and the National Children’s Hospital in Columbus, Fourth vaccine option on the tableBooster dose recommendations by Fall 2022 are important for potential Novavax recipients.

“We really need some guidance,” Sanchez said. “People who are vaccinated with the Novavax vaccine will have an urgent need to get FDA comments on the booster effect.”

“We expect boosters to occur in the fall,” said MPH, ACIP-designated federal officer Melinda Wharton, MD, but “the timeline for that is not yet completely clear.” rice field.

Some ACIP members also expressed disappointment with the labeling of vaccines. Healthcare providers must use the online expiration checker tool because the expiration date is not displayed directly on the vial. Barriers to patient access.

Helen KeippTalbot, MD, MPH, ACIP member of Vanderbilt University in Nashville, admits, “We are moving at warp speed … to make the vaccine available to everyone.” .. “Hopefully, the label will be updated by the time we discuss the boost and immunodeficiency doses for this vaccine.”

The Commission recognized that additional meetings would be needed to clarify the labeling issues and discuss the timeline for boosted immunization of Novavax recipients.

“Today we were able to approve this fourth vaccine candidate, but obviously there is still work to be done,” stressed Grace Lee, MD and MPH, ACIP Chairs of the Stanford School of Medicine in California.

The Novavax vaccine has already been approved for use in other countries, including the United Kingdom and Japan.

  • Amanda Dambrosio MedPage Today’s corporate and research team reporter. She covers obstetrics and gynecology and other clinical news and writes feature articles on the US healthcare system. follow

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2/ https://www.medpagetoday.com/infectiousdisease/covid19vaccine/99804

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