MGH Researcher Bioengineers Perform First-of-its-kind Burn Treatment

health

A state-of-the-art material that sits halfway between solids and liquids allows wounds to be treated with significantly less pain and reduces the risk of life-threatening infections.

Researchers at Massachusetts General Hospital have bioengineered a breakthrough new burn treatment that treats wounds with less pain and reduces the risk of potentially life-threatening infections. Treatment with materials. announced to the hospital on Monday.

this cutting-edge biomaterialsthe first of its kind, is particularly useful for replacing wound dressings in patients who have experienced second-degree burns. Based on an eco-friendly, non-toxic approach designed to eliminate

A hydrogel is usually placed directly over the wound and covered with gauze or other protective dressing. They contain a network of polymers bonded together to form a mesh of highly absorbent material. The idea is to create an environment around the wound that retains water, such a moist environment promotes wound healing, MGH said.

Most current bandages adhere to wounds and in some cases must be surgically removed. The result is “delayed healing and trauma of the newly formed tissue, not to mention excruciating pain for the patient,” says his O. Berk Usta of the Engineering Center. MGH Medical and Surgery said in a statement.

To find a new solution, MGH researchers teamed up with a team from Tufts University. Their goal was to develop a hydrogel that doctors could dissolve quickly when needed, reducing the need for pain relievers, opioids, and long hospital stays that could create a big dent in a patient’s wallet.

According to MGH, the new hydrogel they created can be dissolved within five minutes using a solution that breaks down the molecular structure without harming nearby skin cells. Matter lies somewhere between solids and liquids, mixing properties of both.

When first applying treatment, doctors can create a protective wound barrier in as little as 15 seconds. Current hydrogel preparation methods are time-consuming and potentially dangerous, the hospital said.

“Hydrogel dressings for timely and healthy burn healing have been around for years, but they are far from ideal and represent an area of ​​intense research by scientists and bioengineers. ,” said Ayse Aslihan Gokaltun, surgical instructor at MGH and Harvard Medical School. , in a statement.

The newly developed hydrogels not only offer many benefits for physicians and patients, but may also be readily available to the broader consumer market.

“The simple and rapid method we have developed for synthesizing and assembling hydrogel components allows for large-scale production and low-cost commercialization,” Tufts University researcher Ayse Asatekin said in a statement. And it will pave the way for translating this groundbreaking science into viable therapeutic applications in areas where no standard of care has yet been accepted.”

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