Beer hop compound may help prevent Alzheimer’s disease, study suggests

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FILE – A person holding two handfuls of hops in Quellfurt, Saxony-Anhalt, Germany, September 13, 2021. (Photo by Jan Woitas/Picture Alliance via Getty Images)

A new study suggests that hops, the dried flowering parts of the hop plant used in beer, may have some unique health benefits with respect to Alzheimer’s disease.

Investigation, Published in the American Chemical Society’s Chemical Neuroscience on October 25 The journal reports that chemicals extracted from hop flowers may prevent the aggregation of amyloid-beta protein in the brain, which researchers have strongly linked to Alzheimer’s disease.

The study doesn’t mean you should drink more bitter beer, but it does say that hop compounds may serve as a basis for foods that reduce the risk of neurodegenerative disease.

Alzheimer’s disease, the most common form of dementia, involves the parts of the brain that control thought, memory, and language. It is often characterized by memory loss, which can severely affect the ability to carry out daily activities.

U.S. Centers for Disease Control and Prevention about 6 million Americans People who had Alzheimer’s disease in 2020. Barring medical breakthroughs, that number is expected to double by 2050. Nonprofit Alzheimer’s Association.

The Alzheimer’s Association explains on its website that the disease leads to death of nerve cells and loss of tissue throughout the brain. Over time, the brain shrinks, affecting nearly all of its functions, the nonprofit says.

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Studies have shown that the combination of physical activity, quitting smoking, light alcohol consumption, proper diet, and cognitive activity can reduce disease risk by as much as 60%.

Researchers have not fully elucidated the cause of cell death and tissue loss in Alzheimer’s patients, but it is believed that the main culprit is plaque that accumulates between nerve cells. Formed when fragments of the beta protein aggregate.

“Part of the difficulty in treating the disease is the time lag between the onset of underlying biochemical processes and the onset of symptoms, which can be several years apart,” said the American Chemical Society post. details the new research. “This means that irreversible damage to the nervous system occurs before you know you may have the disease.

The most successful hop extract in lagers and light ales

Because of the time lag, scientists have turned their attention to Alzheimer’s disease prevention strategies. One area is ‘nutraceuticals’, ie foods with some medicinal or nutritional function.

Hop flowers, which are used to flavor beer, have been investigated as one of these potential dietary supplements. Recent research suggests Bitter hop acids may improve cognitive function, alertness, and mood in older adults. Other studies show that plants At least in mice, it may interfere with the accumulation of amyloid beta protein associated with Alzheimer’s disease.

In a new study, researchers Cristina Airoldi, Alessandro Palmioli, and colleagues at the University of Milano-Bicocca sought to investigate which compounds in hops have this effect.

File – A man holding a glass of beer in a hop field. (Photo by Armin Weigel/picture Alliance via Getty Images)

Researchers tested four common hops found in beer. They found that the extract was able to prevent amyloid beta protein from clumping in human nerve cells in laboratory dishes.

The most successful extract is from Tettnang hops, the researchers report, found in many types of lagers and light ales.

While the findings in no way justify drinking more bitter beer, researchers say hop compounds could serve as the basis for foods that reduce the risk of Alzheimer’s disease.

This research Italian Ministry of University Research (MUR).

This story was reported from Cincinnati.

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