Health
Sponges may hold next-generation COVID treatments
We’ve come a long way since our early days COVID pandemic. Not only is it effective vaccine and booster But cures have also been found in unexpected places like SpongeBob SquarePants.
so Research published Jan. 9 in the journal antiviral research, Researchers at the University of British Columbia have identified 26 compounds found in sponges, plants, bacteria and other marine organisms that are effective in fighting COVID infection. This finding could lead to more effective antiviral treatments against the novel coronavirus.
“This multidisciplinary research team is unlocking the significant potential of biodiversity and natural resources to discover nature-based solutions to global health challenges such as COVID-19,” said UBC’s said François Jean, a microbiology and immunology researcher and senior author of the study. in a statement.
The team’s new discovery began with an initial study of a catalog of over 350 compounds from a variety of natural sources. Human lung cells were then placed in a solution made with the compound before infecting the cells with COVID-19. From this process, we were able to narrow down the list of compounds of interest to 26 that could completely reduce viral infection of lung cells.
The authors of this study collected compounds from sources around the world, but the three most effective came from Canadian backyards. Bafilomycin D from BC marine bacteria. Holilin A is also derived from a Newfoundland marine bacterium. So it looks like there’s something (literally) in the waters of the Great White North, right?
“The advantage of these compounds is that they target cells rather than viruses, block viral replication and help cells recover,” said a microbiology and immunology researcher at UBC, in a statement on the study. rice field. She added that because the compound targets human cells rather than viruses, it could be effective against not only influenza but future subspecies.
The researchers now plan to build on their findings by testing the compound on animal subjects next year. It offers a new light of hope in the future.
“Our study also paves the way for large-scale testing of natural product medicines that can block infections associated with other respiratory viruses of great concern in Canada and around the world, such as influenza A and RSV. I have,” said Jean.
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