Health
Antibiotics may increase risk of Crohn’s disease
Antibiotics are one of the most common drugs that help prevent bacterial infections. However, recent studies have revealed how antibiotics increase the risk of new disease. Inflammatory bowel disease (IBD) Ulcerative colitis and Crohn’s disease.
A collaborative study by the Karolinska Institute in Sweden and the Harvard Medical School was recently published Lancet Gastroenterology & Hepatology.. Researchers have observed that drugs containing more microbes increase the risk of IBD.
Inflammatory bowel disease is becoming more common in Western countries and developing countries. More research focused on the role of the intestinal microbiome in overall health raises concerns about antibiotics that cause damage because drugs can cause gastrointestinal disease.
by Clone & Colitis Foundation, More than 700,000 Americans have Crohn’s disease. It commonly affects the small intestine, but can occur in other parts of the digestive tract.
Crohn’s disease Gastrointestinal inflammation is generally mild to severe and can cause pain, diarrhea, fatigue, and malnutrition. The disease is acquired genetically or is caused by viruses or harmful bacteria that attack the immune system.
There is no cure for Crohn’s disease or other IBD, but patients are generally treated with antibiotic therapy or anti-inflammatory drugs. However, frequent antibiotic use can be harmful in the long run.
History of antibiotics
Antibiotic treatment It has been around since ancient history from natural sources such as plants and moldy bread as used by the ancient Egyptians. Antibacterial chemistry was developed only in the 19th century until the early 1900s. In 1909, the German doctor Paul Ehrlich discovered that the chemical substance arsphenamine could be used to treat syphilis and created the first chemotherapy or chemotherapy.
(Photo: Getty Images)
After that, antibiotics were commercialized in the 1930s, Pronto sill It was developed in Germany only a few years after Alexander Fleming discovered that penicillin could treat bacterial infections. It was.
Dr. Long Nguyen of Harvard Medical School confirmed that “antibiotics that negatively affect the intestinal microbial community are risk factors for IBD.” This is the first study to support what experts have doubted for a while.
read: Princeton researchers discover “Poison Arrow” antibiotics that resist immunity
Increased risk of Crohn’s disease
With an enhanced epidemiology (ESPRESSO) database in the Swedish histoPathology report, the team collected approximately 24,000 IBD cases. One-third of the patients had Crohn’s disease and the rest had ulcerative colitis. They were compared to 28,000 siblings and over 100,000 healthy controls.
The Swedish population is subject to universal drug treatment, said pediatrician Jonas Ludobigson, who is also a professor at the Karolinska Institute. “This makes the Swedish registry ideal for studying IBD risk factors.” About 1% of the population suffers from IBD, which is associated with cancer and death.
(Photo: pxfuel)
Understanding risk factors for inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease may help health professionals find ways to prevent these diseases, Ludobigson said. “This study provides another puzzle piece and more reasons to avoid unnecessary use of antibiotics.”
read more: Ancient Organisms: A 1,000-year-old medical manuscript uses garlic and onions as a cure to kill antibiotic-resistant BActeria
Check out other news and information Medical conditions Science Times.
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