Health
Risk of severe COVID can affect the type of asthma
Grayson agrees with Clana that in the early days of the COVID-19 pandemic, there were many concerns that asthma could be a risk factor. Coronavirus attacks the lungs..
But everything that has arisen from the first epidemic in China suggests that asthma is not a risk factor for life-threatening COVID, and data continued to confirm it as the coronavirus spread worldwide. ..
“It’s not in the data. With it, it’s a very small risk. It’s not something I can see,” he said.
Researchers speculate that people with allergic asthma may have some protection against COVID because of the way the coronavirus infects the body.
The SARS-CoV-2 virus, which causes COVID-19, invades lung cells by binding to a type of surface protein called the ACE2 receptor, Clana said.
“In allergy type settings inflammation, ACE2 receptor expression appears to be down-regulated. It seems low. There aren’t many receptors, “he said.
Due to the low number of ACE2 receptors available, people with allergic asthma may not be very vulnerable to severe infections, Clana said. She added that this theory could also help explain why other chronic diseases appear to increase the risk of COVID.
“Patients with the following conditions Diabetes mellitus Or High blood pressure, The expression of this receptor is increased. This may be the reason why these comorbidities are at particularly high risk for this infection. “
But that only explains why allergic asthma is not a major risk factor for severe COVID, Grayson said. Some studies do not explain why people with non-allergic asthma are at increased risk.
Grayson believes that the association between non-allergic asthma and COVID found in these studies is actually an association between COVID and many different lung diseases, especially COPD.
“There are studies showing that COPD increases the risk of more severe COVID, not significantly, but not significantly, such as hypertension or diabetes. [being] “It’s actually COPD that they call non-allergic asthma, and I’m worried that it might distort their data,” he said.
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