Confusion may be an early sign of COVID-19: Study

Confusion with fever may be an early symptom of COVID-19.

London:

According to a review of the study, delirium or confusion with fever may be an early symptom of COVID-19, especially in elderly patients.

A study published in the Journal of Clinical Immunology and Immunotherapy suggests that some patients also develop delirium, along with loss of taste and smell, and headaches that occur in the days before the onset of symptoms of cough and dyspnea. doing.

Therefore, with high fever, the manifestation of this confusion should be considered an early marker of the disease, especially in older patients.

“Delirium is a state of confusion that makes people feel as if they are dreaming and not touching reality,” said Javier Correa of ​​the Open University of Catalonia (UOC) in Spain.

Correa, who conducted the study at the University of Bordeaux in France, said, “Especially in such epidemiological situations, individuals who show signs of certain confusion may be signs of infection and should be wary. There is. “

Correa, along with UOC researcher Diego Redolar Ripoll, reviewed a scientific study published on the effects of COVID-19 on the central nervous system, the brain.

The review found that the new coronavirus also affected the central nervous system, increasing signs of neurocognitive changes such as headaches and delirium, as well as psychotic episodes.

“The main hypotheses that explain how the coronavirus SARS-CoV-2 affects the brain are hypoxia or neurooxygen deficiency, inflammation of brain tissue due to cytokine storms, and the ability of the virus to pass through the blood. It shows three possible causes of the fact that it has-a brain barrier to invade the brain directly. “

He said that any of these three factors can cause delirium.

Evidence of hypoxia-related brain damage has been observed at autopsy performed on patients who died from the infection, and it is possible to isolate the virus from brain tissue, Correa said.

According to researchers, delirium, cognitive deficits, and behavioral abnormalities are most likely the result of systemic inflammation of organs and hypoxia, causing inflammation of nervous tissue and damage to areas such as the hippocampus.

They said this was associated with cognitive impairment and behavioral changes presented by patients suffering from delirium.

(This story has not been edited by NDTV staff and is automatically generated from the syndicate feed.)

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