Health
Another study casts doubt on “convalescent plasma” as a treatment for COVID-19-Consumer Health News
Wednesday, November 25, 2020 (HealthDay News)-In the early stages of the COVID-19 pandemic, case reports help very sick patients inject plasma from those who survived the disease to boost results. Suggested that it might be.
However, the findings released on November 24 New England Journal of Medicine, Along with disappointing results from previous trials, suggests that their first hope may be unfounded.
The new study was carried out by Argentine researchers. We compared the outcomes of 228 inpatient COVID-19 patients who received so-called “convalescent plasma” and 105 patients who did not (“placebo group”). All were very ill and developed pneumonia.
However, one month later, “no significant difference was found between the convalescent plasma group and the placebo group” in terms of clinical outcome, according to a team led by Dr. VA Simonovich, about 11% of patients with both. Died in the group. Italian hospital in Buenos Aires.
The theory behind the use of survivors’ plasma in people fighting COVID-19 is that plasma contains immune system drugs that may help recipients fight the disease. ..
However, previous studies from India (this time in patients with “moderate” COVID-19) also had little therapeutic benefit in preventing the disease from progressing to more severe stages. ..The study was led by Dr. Anup Agarwal of the Indian Medical Research Council in New Delhi on October 22nd. BMJ..
According to a US expert unrelated to either trial, it may be time to give up convalescent plasma as a viable COVID-19 treatment.
“There were several major trials that showed the same results. Convalescent plasma does not appear to affect the course of COVID-19,” said Dr. Mangala Narasimhan. She is Senior Vice President and Director of Critical Care Services at Northwell Health in New Hyde Park, NY.
Narasimhan also said in an Argentine trial, “Even if you properly measure the amount of antibody they were giving people. [in the transfusions], No merit was seen. “
She believes that other treatments should continue to be the first-line choice for severe COVID-19.
“The new monoclonal antibody provides a more targeted and reliable antibody load in COVID-19 patients and can affect the course of the disease if given early after a positive test,” said Narasimhan. Stated.
For more information
For more information on how to treat coronavirus at home Centers for Disease Control and Prevention..
Source: New England Journal of Medicine, November 24, 2020; Mangala Narasimhan, DO, SVP, Director of Critical Care Services, Northwell Health, New Hyde Park, NY
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