Health
Studies find that too little sleep in middle-aged people may increase the risk of dementia
The correlation is also related to whether people are taking sleeping pills and whether they have a mutation called ApoE4 that increases their chances of developing Alzheimer’s disease, Dr. Savior said.
Pamela Russy, an associate professor of epidemiology and community health at the University of Minnesota and not involved in the study, said: “Short sleep is so common that it can be important at the social level, even if it is reasonably associated with the risk of dementia. Short sleep is something we can control and It’s something you can change. “
Nonetheless, like other studies in the field, this study had limitations that prevented it from proving that inadequate sleep could cause dementia. According to experts, most sleep data is self-reported and is a subjective measurement that is not always accurate.
At one point, nearly 4,000 participants measured their sleep time with accelerometers, and the data were consistent with self-reported sleep time, the researchers said. Nonetheless, the quantitative measurements were taken later in the study, when participants were about 69 years old, and were less useful than those obtained at a younger age.
In addition, most participants were Caucasian, well educated and healthy compared to the entire UK population. Researchers may also have missed some cases because they relied on electronic medical records to diagnose dementia. They were also unable to identify the exact type of dementia.
“It’s always hard to know what to conclude from this type of study,” said a professor of geriatric psychiatry at the University College London, one of the few experts who submitted comments about the study to Nature Communications. Robert Howard wrote. “Insomnia-you won’t need anything else to ruminate in bed,” he added. “You shouldn’t worry about them heading for dementia until they fall asleep soon.”
There is compelling scientific theory as to why sleep deprivation exacerbates the risk of dementia, especially Alzheimer’s disease. Studies show that cerebrospinal fluid levels of amyloid, a protein that aggregates in Alzheimer’s plaques, “elevate in sleep-deprived people,” Dr. Musik said. Other studies on tau, another Alzheimer’s disease protein from amyloid, said that “sleep is important for removing protein from the brain or limiting production.”
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