Health
1 in 4 experiences mild side effects from the Covishield vaccine: The Lancet Study
Systemic effects included headache, malaise, chills and tremors, diarrhea, fever, arthralgia, muscle aches, and nausea.
One in four experienced mild, short-term systemic side effects after receiving a COVID-19 prophylaxis (known in India as Covishield) with the Oxford-AstraZeneca (ChAdOx1 nCoV-19) vaccine. To do. Headache, malaise, and tenderness are the most common symptoms. Studies show Was published in Lancet infection journal.
Researchers at King’s College London in the United Kingdom also found that most systemic side effects (meaning side effects except where the injection was made) peaked within the first 24 hours after vaccination, usually 1-2 days. I found that it would continue.
Systemic effects included headache, malaise, chills and tremors, diarrhea, fever, arthralgia, muscle aches, and nausea. Local side effects (meaning side effects when the injection was given to the arm) included pain, swelling, tenderness, redness, itching, warmth, and swelling of the armpits at the injection site.
Analysis of data from the ZOE COVID Symptom Study app found that the general population with both the Pfizer and AstraZeneca vaccines had far fewer side effects than those reported in the study.
“Data should reassure people in their 50s and older, who are usually mild and short-lived with vaccines in the real world, especially at the highest risk of infection,” said the ZOE COVID Symptom Study app and King’s College London. Professor.
Data show 627,383 people from the ZOE COVID Symptom Study app who self-reported systemic and local effects within 8 days of receiving one or two doses of Pfizer or AstraZeneca vaccine between December 8 and March 10. From the user of.
The study also found that side effects were more common among people under the age of 55 and women. Participants with previously identified cases of COVID-19 were three times more likely to have systemic side effects after administration of the Pfizer vaccine than participants without known infections. Patients with previously identified COVID-19 numbers were almost twice as likely to have systemic side effects after the first dose of the AstraZeneca vaccine.
In Phase III clinical trials of the Pfizer vaccine, researchers found that the most common side effects were injection site pain (71-83%), malaise (34-47%), and headache (25-42%). Said. However, actual analysis showed that less than 30% of users complained of pain at the injection site and less than 10% of fatigue and headache after the first dose. Similarly, in a phase III study of the AstraZeneca vaccine, systemic side effects were seen in 88% of young participants (18-55 years) after the first dose, compared with 46.2% after the first dose in this study. A significantly lower rate was seen.
“Our results support the safety of the sequelae of both vaccines, which have fewer side effects in the general population than reported in the Pfizer and AstraZeneca trials, and the safety of those who are willing to be vaccinated. It should help alleviate sexual concerns, “Specter added.
The study also reported a significant reduction in infection rates 12 to 21 days after the first dose of the Pfizer (58% reduction) and AstraZeneca (39% reduction) vaccines compared to the control group. Studies show a 69% reduction in infection at least 21 days after the first dose of Pfizer and a 60% reduction in AstraZeneca.
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