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Estrogen treatment associated with reduced COVID mortality

Estrogen treatment associated with reduced COVID mortality

 


May 18, 2022-Women who received estrogen hormone replacement therapy (HRT) within 6 months of catching COVID-19 had a reduced risk of dying, a new study said.

The study, combined with data showing that men have higher COVID hospitalizations and mortality rates than women, provides more evidence that estrogen may provide broader protection against coronavirus. Regular medicine..

“This study supports the theory that estrogen may provide some protection against severe COVID-19,” said Christopher Wilcox, one of the authors of the paper. Oxford University Press.. “We hope that this study can reassure patients and clinicians that there are no signs of discontinuing hormone replacement therapy due to a pandemic.”

Researchers investigated the medical records of 1,863,478 women from 465 general practitioners in the United Kingdom found in the primary care database of the Oxford-Royal College of General Practitioner Research and Survey Center.

The researchers found 5,451 COVID cases with hormone replacement therapy associated with a 78% reduction in “mortality from all causes.”

The study covered the first 6 months of the pandemic before vaccination became available. Researchers say more research is needed on estrogen levels and COVID cases, including whether estrogen-containing contraception affects COVID risk.

This study shows that women performed better than men in other pandemics, including SARS-CoV and MERS-CoV outbreaks.

“The reason for these gender differences is unknown,” the study said. “A variety of hypotheses have been proposed from patterns of sexual behavioral changes, such as smoking, comorbidities, and gender-related immunological changes. In particular, the role of estrogen in the immune response of women has received much attention. increase.”

A study based on Swedish data published earlier this year BJM open We also found that HRT is associated with a reduced risk of death from COVID-19 in women.

Sources

1/ https://Google.com/

2/ https://www.webmd.com/lung/news/20220518/estrogen-treatment-linked-to-reduced-covid-mortality

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