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An HIV drug that you take only twice a year?

 


Wednesday July 1, 2020 (HealthDay News)-Scientists HIV A drug that can only be taken several times a year.

With a single injection of an drug called lenacapavir, blood HIV levels in a small group of patients. In addition, I was able to maintain the activity level in the blood for more than 6 months.

It all increases the possibilities of the day HIV treatment It only needs to be taken twice a year.

Current treatment regimens for HIV-oral combination Drug Often referred to as “cocktails”-the co-author of the study, Dr. Martin Lee, said they generally work very well.

“But patients often say that taking daily medications can be a burden over time,” said Lee, director of clinical research at Gilead Sciences, which is developing lenacapavir. Stated.

Therefore, more effective HIV treatments are expected to “free people from their daily medications,” Lee said.

More than that, he pointed out that longer-acting drugs could potentially offer an easier way to prevent HIV in people at high risk: Today it is known as Is done with a tablet regimen PrEP (Pre-exposure prophylaxis).

However, much work remains. New research published on the 1st of July in the journal NatureLee said it would provide a “proof of principle” that dosing intervals of 6 months are possible.

Researchers have found that in 40 healthy people, lenacapavir looks safe and can continue to be active in the body for over 6 months. In addition, 32 untreated HIV-infected individuals had lower levels of blood virus within 9 days with a single injection.

Dr. Rajesh Gandhi, an infectious disease doctor at the Massachusetts General Hospital in Boston, is encouraging that the drug is “easy to take every 6 months.”

Gandhi, who is also the president-elect of the HIV Medical Association, agreed that there is a need for longer-acting HIV drugs.

The catch is that HIV isn’t treated with just one drug-as it keeps the virus in check, limiting its potential to become resistant to the drug.

Therefore, to achieve a twice-a-year regimen, Gandhi needs to explain and pair two long-acting drugs.

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