Health
BioNTech Begins Malaria Trial with New Test of mRNA Vaccine
Berlin – BioNTech SE has started human trials. malaria vaccine, A new test of the messenger RNA technology that enabled the most successful vaccination against Covid-19.
The first patient was administered on Dec. 21, chief executive Ugur Sahin said in an interview. The Phase 1 trial will enroll 60 patients and he will use three different doses for one vaccine candidate, said BioNTech’s CEO. The Mainz, Germany-based company plans to evaluate different versions of the shot to see which works best.
A malaria vaccine is one of many new shots BioNTech is testing in patients, and the biotech company will use proceeds from a Covid-19 vaccine it developed with Pfizer to develop an drug. Rival Moderna also says it will pursue a vaccine against malaria.
Malaria has long been a difficult target because the complexity of the parasite that causes it makes creating an effective vaccine difficult. BioNTech’s shots are designed to target several potential antigens in order to “identify the best candidates,” his chief medical officer Ozlem Tureci said in a statement.
The first vaccine for the disease, developed by GSK Plc, prevented only about 40% of malaria cases in large studies. Developed by researchers at the University of Oxford, Second His Shot is currently being tested in a large multinational trial.
According to the World Health Organization, the disease killed about 619,000 people last year, mostly young children in Africa. BioNTech’s planned vaccine production site in Kigali, Rwanda, will help produce a malaria vaccine, Sahin said.bloomberg
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