Health
“AeroNabs” nasal spray promises strong protection against viruses
Key Point
- UCSF scientists believe they may have found a cure for the coronavirus
- Invention based on llama-like Nanobodies that bind to coronavirus proteins
- Can help those who don’t have access to the vaccine or don’t respond well to it
According to researchers at San Fransico, nasal sprays can dramatically slow the spread of COVID-19. They have produced very powerful molecules that can act like traditional antibodies.
Expert University of California San Francisco (UCSF) has discovered a method of deploying antiviral drugs via an inhaler that enters the airways of affected individuals directly. researcher Synairgen Last month, a nebulizer that delivered interferon beta aerosol to the lungs of COVID-19 patients was found to be a potential treatment.
UCSF researchers have designed a nasal drop containing a specific type of neutralizing antibody-like protein that can prevent the new coronavirus from infecting host cells.
Aerosol formulations called “AeroNabs” can be self-administered using an inhaler or nasal spray once a day. AeroNabs helps protect people from SARS-CoV-2 Until there are potential vaccine candidates..
Researchers are actively discussing with commercial partners to speed up manufacturing and clinical trials of this new approach. If successful, they plan to make AeroNabs widely available as an inexpensive over-the-counter drug to prevent and treat coronavirus infections.
AeroNbs co-inventor Peter Walter said, “Much more effective than wearable foam personal protective equipment and a key temporary role until the vaccine provides a more permanent solution to COVID-19. We believe that it is a molecular form of PPE that can fulfill the above-mentioned goals.” , Professor of Biochemistry and Biophysics at UCSF.
They also emphasized that AeroNabs can help people who do not have access to or are unresponsive to the COVID-19 vaccine, which can be a more permanent line of defense against the new virus.
AeroNabs was designed entirely in the lab, but researchers were inspired by Nanobodies – like antibodies Immune proteins found in nature In llamas, camels and related animals. Nanobodies act like antibodies found in the human immune system, but are an effective therapeutic agent against SARS-COV-2.
After analyzing over 2 billion synthetic Nanobodies and finding suitable candidates that could block new coronavirus spike proteins, 21 were included. Three of them were very promising.
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