Health
Childhood obesity treatment reduces long-term health risks, but not depression
When obese children undergo weight loss treatment, the consequences are felt later in life, with a lower risk of serious health problems and early death as they reach young adulthood. However, this is not the case for depression and anxiety, according to research from the Karolinska Institutet. JAMA Pediatrics I will report it.
This study shows that children and adolescents who respond well to obesity treatment may develop obesity-related diseases such as type 2 diabetes, hypertension, and dyslipidemia (abnormally high levels of fat in the blood) as young adults. It shows that the gender is low.
The treatments studied included so-called “behavioral lifestyle therapy,” support for obese children and their families designed to motivate healthy eating, exercise, and sleep habits.
The results are very good news. Because weight loss is difficult to maintain, there is debate about whether treating childhood obesity has long-term health benefits. ”
Emilia Hagman, Professor in the Department of Clinical Sciences, Interventions and Technology
This study shows that obese children who respond to treatment also have a lower risk of early death. Previous research published in PLOS medicine The same research group showed that obese children have a much higher risk of dying in early adulthood and are much more likely to die from suicide or physical illness. Just over a quarter of deaths were related to obesity.
“This highlights the importance of early treatment, as we know that timely intervention increases the likelihood of success and helps reduce the long-term health risks associated with obesity,” Hagman said. says the doctor.
However, the risk for depression and anxiety was not affected by childhood treatment outcomes, the JAMA Pediatrics paper found. Regardless of the outcome of childhood obesity treatment, the risk of anxiety and depression in young adulthood did not change.
“Losing weight has long been thought to reduce symptoms of depression and anxiety, but we now show that this is not the case,” says Dr. Hagman. “Even though there is an association between the two comorbidities, they must be treated in parallel.”
The study included 6,700 people who were treated for obesity in childhood, identified through the BORIS Registry (Swedish Childhood Obesity Treatment Registry), and then followed up as young adults using the Swedish Patient Registry, Prescription Drug Registry, and the cause of obesity. It included more than that. Death notification. A control group from the general population matched for age, sex, and place of residence was also used.
GLP1 analogs have become popular obesity treatments in recent years, but they were not included in the study because they had not yet been approved at the time the study participants were being treated for obesity. As Dr. Hagman points out, it is still uncommon for this type of drug to be given to children.
“I'm in favor of using these drugs because some children struggle with hunger, and these drugs relieve hunger,” she says. “That said, lifestyle therapy remains the cornerstone of all childhood obesity treatments.”
The research group is currently trying to identify the most effective treatment options for different individuals and the health/risk markers that are important for their future health.
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Reference magazines:
Putri, R.R. Others. (2025). Impact of childhood obesity treatment on long-term health. JAMA Pediatrics. doi.org/10.1001/jamapediatrics.2024.5552.
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