Health
Paho's problem is wary of the increased risk of dengue fever outbreak in the Americas
The dengue fever sent by Aedes Aegypti Mosquito comes in four serotypes: DENV-1, DENV-2, DENV-3, and DENV-4. Immunity to one serotype only provides lifelong protection against that particular serotype. This means that subsequent infectious diseases of other serotypes may increase the risk of severe forms of the disease. The appearance or rise of serotypes that were not previously dominant in the region could lead to a surge in cases due to high population sensitivity.
Regional DENV-3 situation
DENV-3 serotypes have been identified in several US countries, including Brazil, Colombia, Costa Rica, Guatemala, Mexico and Peru. In 2024, Argentina reported its circulation and marked the country's introduction of this serotype. In the same year, Brazil and Colombia reported an increase in cases associated with DENV-3, especially among children, and were detected in Central America and other countries in the Caribbean. This serotype is associated with severe forms of disease, even in primary infections, causing concern about their potential public health effects.
Reappearance of DENV-3 increases the vulnerability of populations that have not been previously exposed to this serotype after long absence in certain regions of this region.
Current situation and recommended measures
In 2024, the Americas reported more than 13 million cases of dengue, of which 22,684 were classified as severe (0.17% of total), with 8,186 deaths (0.063% case fatality). In the early week of 2025, 23 countries and regions in the region reported a total of 238,659 cases, with the majority concentrated in Brazil (87%) followed by Colombia (5.6%) and Nicaragua (2.5%). , Peru (2.5%), and Mexico (2.5%). Of these cases, 263 were severe and 23 died as a result of the illness.
PAHO recommends that the country ensure early and appropriate treatment for patients to enhance vector-controlled measurements, improve diagnostic capabilities within the healthcare system, and prevent severe complications. Public education campaigns that reduce mosquito vector exposure and eliminate breeding grounds are also essential.
The role of vaccination and surveillance
Regarding vaccinations, the evidence generated by the manufacturer and published in a study in Main Phase 3 shows that the TAK-003 dengue vaccine, which is used in some countries in the region, is particularly the case for children with no history. indicates low protection against. Infection. This underscores the need to ensure safe vaccinations and maintain continuous monitoring of adverse events that may result from vaccination.
PAHO, along with other serotypes, is closely monitoring the evolution of DENV-3 circulation and will continue to support the state in implementing effective control and response measures against potential outbreaks. It is important that the healthcare system is prepared to manage the expected increase in cases and reduce the risk of severe complications associated with the disease.
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Sources 2/ https://www.news-medical.net/news/20250211/PAHO-issues-alert-on-rising-risk-of-dengue-outbreaks-in-the-Americas.aspx The mention sources can contact us to remove/changing this article |
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