Health
Research shows that daily use of products during pregnancy may affect newborn metabolism
A newly published study by researchers at Emory University, the University of North Carolina at Chapel Hill and Columbia University found that exposure to phthalate esters during pregnancy can affect neonatal metabolism and brain development.
Phthalates are a group of widely used plasticizers, including various cosmetic and personal care products such as shampoos, soaps, and detergents, as well as plastic food and beverage containers. Previous studies have shown phthalates It may affect hormones And suggested that they could be linked Impact on mother's health and baby.
The study, led by researchers at Emory's Rollins School of Public Health, was published on Wednesday. Natural Communicationwas the first to find evidence of how exposure to phthalate ester acids affects baby metabolism at birth.
Main takeout
- Prenatal phthalate levels in the blood of pregnant mothers were associated with low levels of major neurotransmitter precursors (associated with tyrosine and tryptophan metabolism) that are important for neonatal blood brain development shortly after birth.
- Higher prenatal phthalate levels were also associated with reduced information processing (or attention) in neonates and biological changes associated with excitability (or arousal) scores.
- These findings suggest that exposure to phthalate in pregnancy in maternals may affect neonatal metabolism immediately after birth. Furthermore, exposure to phthalate salts while the baby is still in the uterus can also have a permanent effect on the development of the infant's brain.
What experts say
“This is the first study to demonstrate that maternal exposure to phthalate can affect baby metabolome, and we first showed that these biological changes can affect newborn development. This is important because there is a general belief that the placenta protects babies from many harmful substances, but this study actually supports the ability to affect addiction beyond the placenta,” Dr. Hoffman is a recent graduate and a recent graduate of the Epidemiology PhD program at the Rollins School of Public Health.
“When pregnant women are exposed to phthalates, these chemicals not only enter the body, but Disrupts the maternal metabolismhowever, these exposures also affect metabolism and neurobehavioral function in neonates. And we saw that these substances show biological destruction occurring among newborns that further affect the neurodevelopmental system, so we found that they remained in the body after being born.” Dong Hai side, doctorresearch author and associate professor of environmental health at the Rollins School of Public Health.
I'll move forward
Future research could benefit greatly from following babies with measured intrauterine exposure in childhood, allowing scientists to understand whether early exposure to very common chemicals such as phthalates affect brain development throughout childhood and adolescence. Conducting the study in a large, representative cohort of participants will help to confirm and construct these initial findings. Furthermore, future research could closely examine specific molecules identified here, such as tyrosine and tryptophan metabolites, to reduce the effects of intrin exposure to determine exactly how they affect neurons, affect brain development, and to develop intervention strategies.
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Sources 2/ https://news.emory.edu/stories/2025/04/hs-phthalates-and-newborns-02-04-2025/story.html The mention sources can contact us to remove/changing this article |
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