Health
Childhood obesity may increase the risk of multiple sclerosis
Previous studies have estimated that 53% of MS risk is directly attributed to environmental factors and up to one-fifth of MS cases may be attributed to smoking. Smoking and high body mass index (BMI) are the global drivers of many non-communicable diseases, causing significant early morbidity and mortality.
This study was funded by Burt Charity and attended by researchers from Queen Mary University in London, Burt Health NHS Trust, and Oxford University, using published literature from the United Kingdom, the United States, Russia, and Australia. Estimated and predicted percentage. Incidence that may result from two variable risk factors: smoking, high BMI in childhood and adolescence.
This study International Journal of EpidemiologyIn 2015, we found that about 10% of the MS population risk could be attributed to smoking, indicating a corresponding decrease in smoking prevalence. Conversely, the increasing proportion of the population in the countries surveyed is obese, thus increasing the potential contribution of premature obesity to MS incidence. The percentage varies by country, but the same pattern is seen around the world.
In 2015, early highs in BMI were at a higher risk than smoking in the United States and Australia and were comparable in the United Kingdom. The risk of high early life BMI is highest in the United States (11%) and is estimated to increase to 14% by 2035. In the UK, a high early life BMI will account for 10% of the 2035 MS population risk.
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Incidence MS rate due to high BMI in children and adolescents |
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|
2015 |
2025 |
2035 |
|
|
Australia |
9 |
Ten |
11 |
|
UK |
8 |
Ten |
Ten |
|
USA |
11 |
13 |
14 |
|
Russia |
Four |
Five |
6 |
If these observations were confirmed to be causal, the authors found that reducing the prevalence of these modifiable lifestyle risk factors was associated with an increased incidence of MS and other non-communicable diseases. It is likely to have a significant impact.
The corresponding author, Dr. Ruth Dobson of the Wolfson Institute of Preventive Medicine at Queen Mary, said: Smoking and obesity are not the only effects of cancer and heart disease. Focusing on early-onset illnesses such as MS, lifestyle choices may be more resonating with younger people who may influence the risk of future illness. “
The limitation of this study is that it is an observational analysis of the data and does not determine the probability of a direct causal association of smoking or high BMI on the incidence of MS.
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