Bongani Nkoshi 
3 hours ago
Johannesburg-Medical experts say that the drug ivermectin may be judged to be effective in treating Covid-19, but the general public has to wait for the results of ongoing trials. There is.
Six doctors from the Stellenbosch University (SU) School of Medicine, Kaericha Hospital, and Tygerberg Hospital published an article in the journal entitled “Covid-19 Ivermectin: Promising but Not Definitive” I wrote it.
Roland van Rensburg, Eric H Decloedt, Helmuth Reuter, Arifa Parker, Neshaad Schrueder and Sa’ad Lahri participated in a fierce debate about the efficacy of drugs registered for use only in South African animals.
Some organizations have accused the government of permitting drugs for humans. They claimed it was effective against the coronavirus.
SU experts specializing in medicine and clinical pharmacology have investigated the efficacy and safety results of ivermectin in the treatment of Covid-19 by several randomized controlled trials (RCTs) and observational studies. Is written.
“Ivermectin data from larger RCTs are expected in early 2021,” they write. “These data are very promising and show a significant therapeutic effect and acceptable side effect profile of ivermectin on Covid-19, especially when combined in a meta-analysis.”
Several scientific studies are “certainly promising, but caution is needed as no conclusions have been reached yet,” the six write.
“As a recent example, the widely declared benefits of hydroxychloroquine and chloroquine from observational studies have proven unfounded in larger RCTs,” they said.
Experts pointed out that the Ministry of Health released its own summary of evidence in December.
Based on the data available at that time, it was concluded that ivermectin should not be used in adults with Covid19.
“Nevertheless, rapidly evolving data may now be interpreted as inconclusive based on methodological factors and the small sample size of individual studies, but the combined tendency of the results is that ivermectin It shows promising direct therapy for Covid-19, “said the six.
One of the superior aspects of the study was the optimal dose of ivermectin in humans.
“While higher than standard ivermectin doses appear to be safe in humans, at the time of writing, there are still many human doses required to achieve a balance between antiviral activity and favorable benefits and risks. There is uncertainty, “they wrote.
Tissues that have requested human administration of ivermectin include Black First Land First, the New Economic Rights Alliance, and the Afri Forum.
The AfriForum threatened a lawsuit against the government over drugs.
“Extensive studies in different countries have shown that ivermectin may be effective in treating Covid-19,” the group said.
SU experts urged public and medical professionals to gather behind the medical interventions already underway “while waiting for data from SA or overseas clinical trials.”
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