Health
UCLA: Common Blood Pressure Drugs Do Not Increase COVID-19 Risk
Los Angeles, CA — An international research team co-led by a professor at the UCLA Fielding School of Public Health found that two widely used blood pressure medications have not linked to an increased risk of COVID-19 infection or complications. I found that.
According to Dr. Marc Suchard, a professor of biostatistics at UCLA Fielding School, this type of study is the largest of its kind, using antihypertensive drugs to study groups of more than 1.1 million patients in the United States and Spain. did.
Researchers published in the peer-reviewed journal The Lancet Digital Health found that COVID-19 diagnosis, hospitalization, or subsequent complications for users of either angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers. We have found that the risk of (ARB).
“People with hypertension have worse COVID-19 results, and there remains speculation that some antihypertensive drugs may be harmful,” Suchard said. “The clear answer is that ACE inhibitors and ARBs do not increase risk compared to other treatments.”
The findings support recent regulatory and clinical recommendations that patients should not discontinue ACE inhibitors or ARB therapy due to concerns about increased risk of COVID-19.
“Based on our results, if there is a difference in risk, it will be insignificant and it will be very difficult to refine further outside of such a large international study,” Suchard said.
The team included more than 30 scholars from more than 20 universities and research centers, including UCLA, Columbia University, Oxford University, Yale University, and the University of Dundee in the United Kingdom.
“By comparing people exposed to ACE inhibitors and ARBs with people taking other antihypertensive drugs, either alone or in combination, the safety of these drugs using two methods across three databases. 1,280 comparisons were generated to assess sex, with very consistent results, “said the collaborators. Author Dr. Daniel Morales, Researcher at the University of Dundee.
Research funders include Wellcome Trust, National Institutes of Health, National Institutes of Health, US Department of Veterans Affairs, Korean Ministry of Health, Australian National Health Medical Research Council, and European Health Data and Evidence Network.
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