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NIH investigates rare allergic reaction to COVID vaccine

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Stephen Ryneberg
Health Day Reporter

Thursday, April 8, 2021 (HealthDay News)-New Clinical trial Investigate whether people with strong allergies or known as mastocytosis are at high risk of suddenness Allergic reaction To Moderna or Pfizer COVID-19 vaccine..

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), said:

“The information gathered during this trial will help doctors advise the risks and benefits of vaccination with these two vaccines for people with allergies and mastocytosis, although most of them. For humans, the benefits of the COVID-19 vaccine far outweigh the risks, “Fauci said in a NIAID news release.

A systemic allergic reaction to a vaccine occurs in one or more parts of the body away from the injection site.

Mast cell damage is caused by abnormal, overactive, or both types of white blood cells. It is at risk of a life-threatening reaction that looks like an allergic reaction.

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Researchers will also look at the biological mechanisms that trigger the reaction and whether there is a way to predict who is most at risk.

The Moderna and Pfizer COVID-19 vaccines have been given to millions of Americans. Most of the rare and serious reactions occurred in people with a history of allergies.Many of them had previously called life-threatening allergic reactions Anaphylaxis, The researchers pointed out.

The new study enrolls 3,400 people between the ages of 18 and 69. According to NIAID, up to 35 allergy research centers nationwide will participate.

By design, approximately 60% of study participants should have a history of severe allergic reactions or be diagnosed with mastocytosis. I won’t do the rest.

Participants are shots of Pfizer or Moderna, or placebo Then either vaccine.

Researchers say that about two-thirds of participants will be women because of severe allergic reactions to vaccines, especially the Moderna and Pfizer COVID-19 vaccines, in women.

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Researchers will find out how many participants in each group have a systemic allergic reaction within 90 minutes of injection.

Results are expected towards the end of this summer.

For more information

For more information on the safety of the COVID-19 vaccine, please visit: Centers for Disease Control and Prevention..

Source: National Institute of Allergy and Infectious Diseases, News Release, April 7, 2021

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