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Pfizer may have antiviral COVID-19 pills available by the end of the year

Pfizer may have antiviral COVID-19 pills available by the end of the year

 


With Pfizer and Moderna Developed success mRNA vaccine Against COVID-19 at the end of last year Announced on Tuesday By the end of the year, we should have been able to prepare an oral drug to treat COVID-19 as soon as the patient showed symptoms. The announcement was made by CEO Albert Bourla on the CNBC program Squawk Box, stating that the drug must first work well in clinical trials and be approved by the Food and Drug Administration (FDA) before it can be made publicly available. I did. ).

“This is an inhibitor of the SARS-CoV-2 protease enzyme and is promising in preclinical studies that block the ability of the virus to replicate,” said Dr. Monica Gandhi, an infectious disease doctor and university medical professor. I am. The University of California, San Francisco told the salon by email.

Pfizer has announced that Phase I trials, the first phase of new drug trials, will soon begin to see if the virus is safe for adults.

“It’s a” promising “oral antiviral drug,” Gandhi said. “It’s easy to use to treat COVID-19 in an outpatient environment.”Remdesivir is the only other Existing antiviral drugs Used to fight COVID-19.The famous one Administration To President Trump when he was infected with the virus.

Dr. Russell Medford, chair of the Global Health Innovation Center and the Global Health Crisis Coordination Center, said the drug “has great promise as a treatment that may be used in the first signs of infection or exposure to the SARS-CoV2 virus. I’m holding it. ” There is a warning that the clinical trial process has barely begun.

“It is very ambitious to make this drug widely available by the end of the year, but it is unprecedented, as illustrated by the extraordinary speed with which multiple COVID-19 vaccines have been developed, tested and deployed. That’s not the case, “added Medford.

Such drugs were given to people infected with COVID-19 and were unvaccinated or groundbreaking cases, so their usefulness may be slightly more limited than vaccines. Dr. Alfred Somer, Honorary Dean of the Johns Hopkins University and Professor of Epidemiology, said that prevention of illness by vaccination is more cost-effective than treatment after a person is infected and diagnosed.

Pfizer, like Modana, is currently distributing vaccines using an innovative new technology called mRNA vaccines. Traditional vaccine platforms take weak or dead versions of pathogens (causes of disease) and inject them into the body, whereas mRNA vaccines recognize proteins associated with microscopic invaders. Just use a custom RNA strand to train your body’s cells. For their COVID-19 vaccine, the immune system is trained to recognize proteins associated with spikes protruding from the central sphere of the virus, such as sea urchin spines.


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