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Researchers at Northwestern University have created a new antibody test that detects antibodies to SARS-CoV-2, the virus that causes COVID-19. A minimally invasive test requires a drop of blood with a finger prick.

Antibody tests help determine if someone has been previously exposed to the virus. It does this by detecting the presence of IgM and IgG antibodies that are produced when the body is infected with foreign viral proteins.

Currently, there are limited rapid and reliable antibody tests that do not require intravenous blood. The antibody test being studied at Northwestern was developed in hopes of filling that gap in the test.

In their test, drops of whole blood collected from a finger stick are stored on special filter paper and dried. The blood is then examined using a method called enzyme-linked immunosorbent assay (ELISA) to see if it contains antibodies to specific SARS-CoV-2 proteins that cause a strong reaction from the body’s immune system. I will.

So far, the finger stick test has shown promising results compared to traditional blood sampling.

The team is currently planning to test additional samples to determine exactly how well the antibody test works. In addition, the research team is building a web-based platform to increase antibody testing across Chicago.

Extensive testing using this fingerprick method also means that people can take their blood sample at home and send it to the laboratory by mail. “By not requiring people to come to the clinic to draw blood, we save clinical resources, keep people safe at home in shelters, and significantly expand the potential reach of antibody testing. Yes, ”says Dr. Thomas McDade. Press Release, a bio-anthropologist at Weinberg University of Arts and Sciences and the lead author of research presentations.

The team article is Available on MedRxiv..

Find out more about the test.

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