Health
IIT researchers develop methods to prevent memory loss due to Alzheimer’s disease
The team argues that their study provided another avenue that could prolong the development of Alzheimer’s disease.
A team of four members has been studying Alzheimer’s neurochemical principles. We are looking for new ways to prevent the accumulation of neurotoxic molecules in the brain. This is associated with short-term memory loss by Alzheimer.
This work has been published in well-known international journals such as ACS Chemical Neuroscience, RSC Advances of the Royal Society of Chemistry, BBA, and Neuropeptides.
“Development of treatments for Alzheimer’s disease is especially important for India, which has the third highest number of patients with Alzheimer’s disease in the world, killing more than 4 million people after China and the US. It only reduces some of the symptoms of the disease, but there is still no destructive treatment that can cure the underlying cause of Alzheimer’s disease, “says Vibin Ramakrishnan, professor of biological sciences at the institute.
The disease “about 100 potential drugs for the treatment of Alzheimer’s disease” failed between 1998 and 2011. This shows the severity of the problem. He investigated interesting methods, such as the application of low-voltage electric fields and the use of “ Trojan horse peptides, “to prevent aggregation of neurotoxic molecules in the brain,” he added.
According to Harshal Nemade, a professor of electronics and electrical engineering, the team found that applying a low-voltage, safe electric field can reduce the formation and accumulation of toxic neurodegenerative molecules that cause short-term memory loss in Alzheimer’s disease.
“We have found that an external electric or magnetic field modulates the structure of these peptide molecules, thereby preventing aggregation. Exposure to an electric field can delay neuronal degeneration by 17-35 percent. Objective In general, this delays the onset of the disease by about 10 years.
“But it will require testing in animal models and clinical trials before bringing such new therapeutic approaches to human treatment,” he added. PTI GJS GJS SMN
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It’s a sequel.
It’s a sequel.
Disclaimer:- This article has not been edited by Outlook staff and is automatically generated from the news feed. Source: PTI
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