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Osteoarthritis remains a global public health concern, the study says.

Osteoarthritis remains a global public health concern, the study says.

 


According to data from the 2019 World Disease Load Study, osteoarthritis (OA) is still prevalent worldwide and is expected to increase due to increased obesity and an aging population.

Osteoarthritis (OA) is still widespread worldwide Arthritis and rheumatology..

Age-standardized prevalence (ASR) and OA trends over time are expected to continue to increase, the report said.

To reach this discovery, the author collects data from the 2019 World Disease Burden Study and uses the ASR and its Estimated Annual Rate of Change (EAPC) to age group, gender, region, country, region, and relationships. Joints — Knees, hips, hands, and other joints that do not include the spine.

Site-specific OA data came from 204 countries and territories between 1990 and 2019. According to the author, this was the first time these data were used to analyze the secular trend of OA prevalence.

The authors found that the prevalence of OA increased by 113.25% worldwide in almost 30 years, doubling from 247.51 million in 1990 to 527.81 million in 2019.

In ASR, EAPC increased by .12% (95% CI, 0.11% -0.14%). Overall, ASR increased slightly from 6173.38 per 100,000 in 1990 to 6348.25 per 100,000 in 2019. ASR specific to the associated joint increased in knee, hip, and other joint OA, but decreased in hand OA. The EAPC was 0.32 for the knee, 0.28 for the hip, 0.18 for the other joints, and -0.36 for the hand. It has been noted that knee OA contributes most to the overall burden, and hip OA has shown the highest EAPC in most regions.

“Osteoarthritis of large joints such as the knees and hips is thought to cause the greatest disability and may require joint replacement at the end of the stage if possible, resulting in a significant burden of the disease. It shows the percentage, “explained the author. They later added that “relatively low prevalence and conversely severe severity distribution and hip sequelae can lead to such conclusions compared to other larger joints.”

OA is more prevalent in women, with prevalence increasing with age. The prevalence of OA is high in countries with high SDI levels (more developed countries), which was pointed out in previous studies, so the Social Population Statistics Index (SDI) also played a role.

The authors cited the body mass index (BMI) as a potential factor in changing regional data.

“Geographical diversity of OA prevalence may be associated with the distribution of obesity in adults, as higher BMI (eg, overweight / obesity) is a substantial risk factor for OA.” The author said. “In addition, epidemiological and genetic studies have demonstrated that OA has a multifactorial component in both ecology and genetics and contributes to geographical diversity.”

They said the prevalence of obesity has almost tripled since 1975. According to the World Health Organization (WHO), more than 1.9 billion adults and more than 340 million children and adolescents were overweight or obese in 2016.

Population growth and aging were also cited as factors in the increase in OA prevalence. According to WHO data, the world’s population increased by 45% from 5.32 billion in 1990 to 7.71 billion in 2019. In addition, the percentage of people over the age of 60 increased from 9.2% to about 13.5% in the same time frame.

According to the authors, ligament-related joint injuries can lead to joint degeneration and may contribute to increased prevalence of OA and increased awareness and diagnosis of OA compared to 1990. ..

“Public awareness of correctable risk factors and potential education programs for preventive disease outbreaks are essential to reduce the enormous burden of OA,” the author said.

reference

Long H, Liu Q, Yin H, et al. Prevalence Trends in Site-Specific Osteoarthritis from 1990 to 2019: Discoveries from the 2019 World Disease Burden Study. Arthritis Ryumu.. Published online March 2, 2022. doi: 10.1002 / art.42089

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