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Even mild cases of COVID-19 can damage the brain: studies

Even mild cases of COVID-19 can damage the brain: studies

 


Whether you were hospitalized for COVID-19 or slowed down slightly by a mild case, the virus May have changed your brain tissueAccording to a new study.

A researcher led by a team at Oxford University compared brain scans of people infected with COVID-19 with those not infected, according to a study published in the journal Nature on Monday.

Of the 785 British participants between the ages of 51 and 81, just over half caught the virus, most often during an alpha variant epidemic.The image came from UK Biobank DatabaseIt dates back to 2014 and therefore provides an ideal pre-pandemic “pre-” scan.

“We were in a unique position to use UK Biobank resources to investigate changes that occurred in the brain after a mild (rather than moderate or severe) SARS-CoV-2 infection.” Said The lead author of this study, GwenaĆ«lle Douaud, a professor of clinical neuroscience at Oxford University.

“96% of participants were mildly infected, but on average 4.5 months after infection, the amount of gray matter was significantly reduced and the infected participants’ tissues were damaged.”

When assessing the scan, the researchers compared subjects with matching traits in terms of age, gender, baseline test date, and health issues.

According to Douaud, most of the changes in the brain were found in areas related to the sense of smell. All adverse effects were more pronounced in the elderly.

The study also found that people infected with COVID-19 had an overall reduction in brain volume and poor performance during cognitive follow-up tests.

The data suggested that the tissue damage of 15 people admitted with COVID was worse than those who experienced mild cases, but Douaud said the sample size was too small to be definitive.

Although the causes of brain changes are not yet known, some practical theories include a type of “sensory deprivation” that can be caused by tissue COVID-related inflammation and the effects of the virus on the sense of smell. Is done.

“An important question for future brain imaging studies is to see if this damage to the brain tissue will resolve in the long run.” Duo said..

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