Health
Scientists Develop Inexpensive “Lab-on-Chip” That Detects Covid-19 Antibodies in Less Than 30 Hours — RT World News
Japanese researchers have developed a low-cost Covid-19 antibody test that is microchip-compatible and provides results in less than 30 minutes without the need for medical training. This is a potential game changer to fight a pandemic.
Okinawa Institute of Science and Technology Graduate University (OIST) team Release Their proof-of-concept study in the journal Biosensors and Bioelectronics.
Their device tests diluted plasma for the presence of Covid-19 antibodies illuminated with a fiber optic light probe using tens of thousands of small gold spikes that are smaller than the wavelength of light.
Riccardo Funari, the first author of the new study and post-doctoral researcher at OIST’s Micro / Bio / Nanofluidics Unit, says the current antibody-testing weapons are facing two problems. Testing is accurate but time consuming, expensive and requires expertise. Or it’s easy to use, quick and portable, but inaccurate.
also at rt.com
New nanosensor can detect cancer from a single drop of blood
Therefore, rapid, inexpensive but accurate antibody testing is important for informed and understanding of viruses and their spread throughout the population, guiding coherent public health policies, socialization and travel. Allows for relaxation of restrictions based on information such as.
The researchers argue that their new test detects the lowest possible but clinically relevant antibody concentration and provides results within just 30 minutes.
In addition, this device is inexpensive to manufacture and eliminates the need for technically skilled lab workers, increasing the potential for more comprehensive national testing.
In addition, the device provides quantitative information about the total number of antibodies produced by a particular immune system, which can provide useful information during the research and development of current and future generations of vaccines, further expanding its applications. To do.
“The more antibody that binds, the greater the wavelength shift of the absorbed light,” says Funari. “The fiber optic probe is connected to a photodetector that measures this shift. We can use that information to determine the antibody concentration in plasma samples.”
Immediately when the device can withstand more stringent clinical trials, medical staff can monitor the immune response of patients or participants in vaccine trials in near real-time accuracy.
The device can also identify potential donors for vaccine research and treatments.
Researchers want to expand the test to detect multiple different types of antibodies before testing actual patient samples at hospitals and healthcare facilities near Okinawa.
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