Children born to pregnant diabetic mothers may be 30-80% more likely to develop a heart condition: Study

According to researchers, heart disease in teenagers and adolescents may be associated with exposure to diabetes in utero. Their analysis of young adults and teenagers whose mothers had diabetes during pregnancy found that children had 50-200% higher heart disease than children who were not exposed in utero before the age of 35. It is clear that there was a risk of developing the disease.

The three most common diagnoses among children exposed to diabetes were hypertension (8,713), type 2 diabetes (3,568), and ischemic heart disease (715). According to research author Dr. Jonathan McGabock of the Institute for Children’s Hospital in Manitoba, Canada, and an associate professor at the University of Manitoba, children born to pregnant diabetic mothers are 30 to develop heart conditions. It turned out to be 80% higher. , And are 2 to 3.4 times more likely to develop risk factors for heart disease (high blood pressure, diabetes, etc.) than children born to mothers without diabetes during pregnancy. Heart condition and risk factors diagnosed 2 years ago Children exposed to diabetes in utero.

The team examined data on 293,546 children born to 189,939 mothers in Manitoba, Canada, between 1979 and 2005. Previous studies have recorded an increased risk of type 2 diabetes due to intrauterine exposure to diabetes in utero. The current cohort provided data for 3,628,576 man-years, with an average age of 20.5 at the latest follow-up. “It is unclear whether intrauterine exposure of mothers to diabetes is associated with risk factors for cardiovascular disease and associated endpoints in adulthood. We see this potential association in a population-based birth cohort. I looked it up and followed it up to the age of 35, “writing the author of a study published in the Journal of the Canadian Medical Association (CMAJ).

Of the total number of children, 2.8% were exposed to gestational diabetes and 1.1% were exposed to existing type 2 diabetes. During the study, exposure to both types of diabetes became more common, and this trend was seen elsewhere in the world. Children exposed to diabetes in utero are born to older mothers, are born larger due to gestation, are born prematurely, and may live in rural areas or households with greater socio-economic poverty. The report states that it is expensive.

“In this population-based administrative birth cohort study, fetal exposure to gestational diabetes or type 2 diabetes in mothers was 1.27 and 1.48 times higher risk and 1.85 and 3.38 times higher risk of cardiovascular disease, respectively. Risk factors for cardiovascular disease before age 35 are higher than those who were not exposed to diabetes in utero, which was associated with risk. In addition, the first cardiovascular disease-related outcome is gestational diabetes. Or it occurred 2-4 years before offspring exposed to type 2 diabetes in utero. They also said, “The high prevalence of cardiovascular disease in offspring exposed to diabetes in utero is early onset. It is believed to be due to type 2 diabetes and hypertension. These observations indicate that the prevalence of cardiovascular disease in adolescents and early adulthood is associated with exposure to maternal diabetes in utero. It supports our hypothesis.

The research team suggests that these findings may help preventive health care. “Future studies will reproduce these findings in other settings and extend the follow-up of similar cohorts to the elderly, with a long-term relative contribution to cardiovascular disease-related prevalence of intrauterine diabetes. It is necessary to assess whether it is stable across. Screening children with intrauterine exposure to diabetes for cardiovascular risk factors assesses the future burden associated with cardiovascular disease in the population. May be useful, “they conclude.

Disclaimer: This article is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions about your medical condition, always seek advice from your doctor or other qualified healthcare provider.