March 28, 2021
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Health
Studies find that messenger RNA vaccines reduce the risk of asymptomatic infections
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Tande has not reported disclosure of relevant financial information. See the survey for relevant financial disclosures of all other authors.
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Participants who received the messenger RNA COVID-19 vaccine twice were 80% less likely to test positive for asymptomatic SARS-CoV-2, according to actual research results published in. Clinical infections..
Researchers reported that the risk of asymptomatic infection was reduced by 79% after a single dose. Two messenger RNA vaccines approved for use in the United States are manufactured by Pfizer-BioNTech and Moderna.
“People receive routine care and take care of their patients, so Pre-procedure test protocol Like us, they can be reassured that these vaccines reduce the chances of infection in these patients. “ Aaron J. Tande, MD, An infectious disease consultant and associate professor at the Mayo Clinic Medical College told Healio.
“For the broader COVID-19 situation, a significant proportion (some studies estimate that 50% of infections are infected), Asymptomatic or presymptomatic.. This suggests that the vaccine can not only prevent serious illness, but also prevent subsequent infections from people. [who] It is asymptomatic because it is less likely to get infected, “says Tande.
Tande et al. Conducted a retrospective cohort study of asymptomatic adult patients undergoing a total of 48,333 preoperative SARS-CoV-2 screening tests from December 17, 2020 to February 8, 2021. They analyzed the RR for positive SARS-CoV. -Two tests Asymptomatic people People who have been vaccinated compared to those who have not yet been vaccinated.
Positive SARS-CoV-2 test results were 42 (1.4%) of the 3,006 tests given to vaccinated patients and 45,327 tests given to unvaccinated patients. Of these, 1,436 (3.2%) were confirmed (RR = 0.44; 95% CI, 0.33-0.6). The risk of asymptomatic SARS-CoV-2 infection is in individuals at least 10 days after the first dose (RR = 0.21; 95% CI, 0.12-0.37) and at least 0 days after the second dose (RR = 0.2; 95). It was low. % CI, 0.09-0.44) Compared with unvaccinated individuals.
Tande said further research is needed to address the reduction in COVID-19 infection after long-term vaccination.
“To confirm this and look at specific subgroups of patients, we need to do a larger study. Will people with immunodeficiency have the same results?” Tande said.
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