Health
Genetic mutation studies reveal new coronaviruses to spread rapidly in late 2019
Kate Kerland
LONDON, May 6 (Reuters) -Genetic analysis of more than 7,500 samples infected with COVID-19 suggests that the new coronavirus has rapidly spread worldwide and adapted to its host at the end of last year. The scientists said Wednesday.
A study by scientists at the Institute of Genetics at the University College London (UCL) found nearly 200 recurrent gene mutations of the new coronavirus-SARS-CoV-2-.
Francois Vallou, UCL professor who led the collaboration, said the results showed that most of the global genetic diversity of SARS-CoV-2 was found in the most affected countries. This suggests that the virus has spread worldwide since the outbreak.
“All viruses mutate spontaneously. The mutations themselves are not bad, and there is no suggestion that SARS-CoV-2 mutates faster or slower than expected,” Balloux said. “So far, I’m not sure if SARS-CoV-2 is more or less deadly and contagious.”
According to Reuters, more than 3.68 million people worldwide are infected with the new coronavirus, with 256,000 deaths. The infection was first identified in China in December 2019 and has been reported in more than 210 countries and territories.
Balloux quickly spread worldwide after the UCL team’s findings in Infection, Genetics and Evolution on Wednesday confirmed that the virus had emerged in late 2019.
The survey did not identify the exact starting point or location.
The Balloux team screened the genomes of more than 7,500 viruses from infected patients worldwide. Their results have increased the amount of evidence that the SARS-CoV-2 viruses share a common ancestor since late 2019, when the virus plunged from earlier animal hosts into people. Suggests that.
This means that the virus that causes Covid-19 is least likely to have been in the human circulation for a long time before it was first detected, Balloux said.
A study published by French scientists earlier this week found a man infected with COVID-19 on December 27, almost a month before the first case was confirmed in France.
The World Health Organization said the French incident was “not surprising,” and called on countries to investigate other earlier suspicious incidents.
Balloux said the 198 small genetic changes, or mutations, identified in the study appeared to occur independently multiple times. These may hold clues as to how the virus is adapting and help in efforts to develop drugs and vaccines.
“The main challenge to overcome the virus is that if the virus is mutated, vaccines and drugs may no longer work,” Balloux said. “If we focus our efforts on the parts of the virus that are less likely to mutate, we are more likely to develop long-term effective drugs,” Kate Kelland reports, edited by Peter Graff.
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