Diabetes can worsen the long-term survival of adults with breast cancer

Source / Disclosure The issuer: sauce: Cheung YMM, et al. RF28 | PSUN185. Announcement location: Endo Annual Meeting; June 11-14, 2022; Atlanta (Hybrid Conference). Disclosure: This study was funded by Lily. Add topics to email alerts Receive an email when a new article is posted Please enter your email address to receive emails when new articles are posted .. "data-action " subscribe "> Subscribe The request could not be processed. Please try again later.If you continue to have this issue, please contact us customerservice@slackinc.com.. Return to Healio Atlanta-Study data showed that the presence of diabetes and worsening glycemic control were not associated with breast cancer outcomes until an 8-year follow-up with worse survival in diabetic patients. "For the first five years, glycemic control may not contribute significantly to mortality or cancer progression in most individuals with metastatic breast cancer." YM Melody Cheung, MD, An Endocrinology Fellow at Brigham and Women's Hospital, Harvard Medical School, said at a press conference. "But especially in long-term survivors, diabetes and poor glycemic control were certainly associated with reduced survival." Source: Adobe Stock Cheung and colleagues at the Dana-Farber Cancer Institute identified patients with metastatic breast cancer in a single center between 2010 and 2021 and used the Research Patient Data Registry to determine their diabetic status. The study included data from 244 breast cancer and diabetic patients (median age 57.6 years, 99.6% female, 84.4% white) with age, gender, ethnicity, and hormone receptor status for breast cancer and diabetes. There was a 1: 1 match with no patients. .. Of the diabetic patients, 1.2% had type 1 diabetes, 49.2% had type 2 diabetes, and 15.2% had cancer treatment-related diabetes. In the rest of the cohort, the type of diabetes was unknown. Two years later, the proportion of patients who started a secondary cancer regimen did not differ between patients with and without diabetes. Similarly, overall survival at 5 years did not differ between groups (54% with diabetes and 56% without diabetes). A subgroup analysis found that an 8-year follow-up showed shorter overall survival in people with diabetes (67%) than in people without diabetes (87%). P .047 in 10 years). In addition, poor glycemic control (glycemic levels> 180 mg / dL> more than twice a month) tends to be less likely to be released from secondary cancer treatment after 2 years compared to good controls. Although related, overall survival at 5 years. "Because the clinical effects of diabetes can only be felt over this long period of time, active management of glycemic control may be most relevant to patients with a better prognosis," Cheung said. increase. "Therefore, patients with metastatic breast cancer need to consider individual diabetes goals and strategies that take into account the patient's prognosis." Add topics to email alerts Receive an email when a new article is posted Please enter your email address to receive emails when new articles are posted .. "data-action " subscribe "> Subscribe The request could not be processed. Please try again later.If you continue to have this issue, please contact us customerservice@slackinc.com.. Return to Healio Endocrine Society Sources 1/ https://Google.com/ 2/ https://www.healio.com/news/endocrinology/20220612/diabetes-may-worsen-longerterm-survival-for-adults-with-breast-cancer The mention sources can contact us to remove/changing this article