Health
FDA panel weighing improved booster shots from Moderna, Pfizer
HealthDay Reporter
Monday, June 27, 2022 (HealthDay News)-US Food and Drug Administration Advisory Board vote Whether it is recommended to use the updated COVID-19 booster shot this fall on Tuesday to protect against Omicron and its highly contagious submutants.
The virus mutates so quickly that the FDA may approve new ones vaccination The drug product as COVID-19 cases is expected to surge again this winter. Given how fast the virus changes, the New York Times reported that long human trials may have to be discontinued in order to support more laboratory and animal studies.
According to The Times, human trials can take up to five months and may be discontinued before the vaccine is released to the public.
Both Pfizer and Moderna are testing updated booster shots targeting Omicron variants, and early test results show that fine-tuned shots provide additional protection against Omicron. Since then, subvarieties of Omicron have surfaced and spread. As of June 18, BA.4 and BA.5 subvariants account for 35% of all infectious diseases in the United States.
“Omicron is clearly in the rear-view mirror,” Dr. Peter Hotez, a vaccine expert at Baylor College of Medicine in Houston, told the Times.
Omicron boosters aren’t needed unless they work for the latest Omicron subvariants, but “I’ve never seen any evidence of that,” he said.
Even the FDA said in a briefing document prepared for the advisory board meeting that divalent boosters targeting both the original virus and Omicron were “already somewhat outdated.”
However, Dr. Kelly Moore, president of Immunize.org, a non-profit organization working to increase vaccination rates, told The Times that the accelerated process is already being used for updates. Influenza vaccine Every year.
This is the first time this process has been used in a COVID vaccine, but she says it has been safely administered to hundreds of millions of people.
Updating them could require “very well-informed guesswork,” which she said was “suitable for the situation.”
Nevertheless, the virus may change again and the updated vaccine may become ineffective.
Dr. John Begel, director of clinical research at the National Institutes of Health, told The Times: [the new vaccines] It may be old news by the time autumn comes. “
According to Beigel, one option is to use existing vaccines that continue to provide strong protection against severe illness, with little protection against infection.
According to The Times, the advisory board may be divided between those who believe that fall boosters are widely needed and those who limit additional shots to high-risk individuals.
Dr. Arnold Monto, a professor of public health at the University of Michigan, who chairs the FDA Advisory Board, predicted that booster shots would be provided to a large population.
“We know we’re declining. We have to boost, and it’s better to boost with a more appropriate vaccine than existing vaccines,” Monto told the Times. ..
However, Dr. Paul Offit, a vaccine expert at the Children’s Hospital of Philadelphia and a member of the panel, opposed that idea.
“Hospitalization is declining. Deaths are declining significantly as we are protected from serious illness. That’s important,” Ofitt told The Times.
Since COVID can have serious consequences for these people, it is likely that only people over the age of 70 and over 50 with serious underlying illness will need a fall booster shot, Offit said. I added.
For more information
For more information on the COVID vaccine, please visit the US Centers for Disease Control and Prevention.
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Sources 2/ https://www.webmd.com/vaccines/covid-19-vaccine/news/20220627/fda-panel-to-weigh-improved-booster-shots-from-moderna-pfizer The mention sources can contact us to remove/changing this article |
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