Health
Chinese biotechnology companies are now leading the competition for coronavirus vaccines as testing approaches Phase 3
CanSino Biologics IncThe Chinese biotechnology company continues to be the world leader in the development of the SARS-CoV-2 vaccine. Here’s how they have an advantage over other big pharma companies.
CanSino was founded in Tianjin, China in 2009 after four scientists left Canada’s global pharmaceutical company. They have successfully developed Ad5-EBOV We will continue to develop vaccines for Ebola virus, 16 other vaccines for 13 infectious diseases including COVID-19.
By May, they were the first in the world to publish a human trial, allowing other companies to review their clinical studies. This has become an important step as it allows researchers around the world to evaluate the potential of the vaccine.
Wang Ruizhe, a pharmaceutical analyst at Capital Securities Corp., said the company “deserves to be evaluated for its speed in promoting vaccines through preclinical and human testing.” It tells you something about their ability to mobilize and harness the resources needed to accomplish all of this. The resources needed here are considerable.
Phase I study
In Phase I of the coronavirus vaccine clinical trial, 108 participants had good antibody and T cell responses to the virus. “These results represent an important milestone,” said Wei Chen, a professor at the Beijing Institute of Biotechnology. This study showed that a single dose of the new adenovirus type 5 vector COVID-19 (Ad5-nCoV) vaccine was It has been shown to produce virus-specific antibodies and T cells over days, making it a potential candidate for further investigation.
The immune response was triggered by the vaccine they developed, but it does not guarantee protection against the virus. Dr Chen said there is still a long way to go before the vaccine becomes widely available. At that time, there were about 100 vaccine candidates, and 12 companies were conducting human tests.
Currently, about 36 companies developing vaccines Association of Pharmaceutical Professionals About 23 are conducting clinical trials. Yu Xuefeng, CEO of the former Canadian company Sanofi, who held a senior management role, maintains close ties with the Government of Canada.
“It’s about where Can Sino comes into the game and where other so-called leaders are,” said William Haseltine, a former Harvard HIV researcher. “It’s unclear if everyone crosses the finish line where we can see the safety data we want to see.”
Also read: Genetic vaccines may be at the forefront of healing COVID-19
Promising efforts
A Phase II clinical trial was conducted in Wuhan, where the virus first appeared. They have begun low and medium dose testing of approximately 50 billion and 590 billion viral particles. They are also working at Precision nano systemCompany in Vancouver, aims to develop a mRNA lipid nanoparticle vaccine.
CanSino will soon enter Phase III of its vaccine test. Canada is allowed to produce vaccines if approved for emergency pandemic use in connection with the Canadian National Research Council.
Wang said: “The viral vector that CanSino uses is a relatively safe approach compared to other approaches, but it’s hard to call efficacy right now. Just to make sure things fall apart, There is no shortage of history where promising efforts have reached the final stages of testing.”
Also read: FDA sets guidelines for approval of coronavirus vaccines
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