Health
Compound found in sponges that could stop Covid from infecting human cells
A compound has been discovered in sponges that can stop novel coronaviruses and influenza viruses from infecting human cells.
Researchers have found 26 such compounds in nature, including plants and fungi.
An international research team says their findings pave the way for new antiviral agents that are more than useful in treating the virus.
They argue that because the compounds target human cells, which evolve more slowly than viruses, they could help deal with existing and future variants and influenza.
They are effective in very small doses and completely stop viral infection in cells, the team added.
Co-first author of the study, Jimena Pérez-Vargas, Ph.D., of the University of British Columbia, Canada, explains: Recover.
“Human cells evolve more slowly than viruses, so these compounds may work against future variants and other viruses, such as influenza, if they use the same mechanisms.”
For this study, the team investigated over 350 compounds derived from natural sources such as plants, fungi and sponges to find new antiviral drugs that could be used to treat new diseases.
They soaked human lung cells in a solution made from these compounds and infected the cells with Covid.
It found that 26 compounds completely stopped coronavirus infection in cells.
The researchers made their discovery using a version of the coronavirus that turns cells bright green when infected, and a special screening technique.
They say fluorescent viruses allow scientists to check thousands of compounds and track viruses as they move from one cell to another, a highly laborious procedure that previously had to be completely tedious. It is said to be a powerful tool that can perform
All three of the most effective compounds were found in Canada. Arotaketal C from sponges collected in Howe Sound, British Columbia; Bafilomycin D from marine bacteria collected in Berkeley Sound, British Columbia; and Holilin A from marine bacteria collected off Newfoundland. .
Further trials showed that the three compounds were effective against the Delta variant and some Omicron variants and were almost as safe as existing Covid treatments.
Many of these treatments are no longer effective against the currently circulating Omicron subspecies as the virus has evolved.
This highlights the need for new antiviral agents, the team said.
Bafilomycin D was found to act synergistically with existing antiviral nasal sprays and against Omicron subvariant BA.2.
This paves the way for multi-drug treatments that work against coronaviruses and other common viruses.
The team now hopes to test the compound in animal models within the next six months.
The lead author of the study, Dr. François Jean of the same university, added: As influenza A and RSV. ”
The findings were published in the journal Antiviral Research.
|
Sources 2/ https://www.independent.co.uk/news/health/covid-cure-prevention-sea-sponge-discovery-b2258510.html The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]
 |
 |
 |
