Health
Demand for cholera vaccine soars – this company may have the solution
Three pharmaceutical manufacturers will also join the mission to restock their production lines.
IVI plans to transfer its simplified vaccine technology to Indian company Biological E and South Africa's Biovac, which will significantly boost vaccine production in sub-Saharan Africa.
Experts say the process could take another 18 months to two years. Meanwhile, India's other major company, Bharat Biotech, is working on developing its own vaccine and could be able to replenish supplies by the end of 2025.
If all goes as planned, Eubiologics should increase its production capacity to 80 million doses next year, Park said, with Bharat adding another 15 million doses, bringing total annual global supply to 95 million. It is expected to go from 100 million doses to 100 million doses, it added.
“It won't be enough for a preventable campaign either, but I think we'll be in a good position in two years,” she said.
The vaccine shortage, which has put the world's health organizations at a disadvantage, underscores the difficulty of fighting the epidemic.
“Blue Death”
Cholera is an acute intestinal infection that is spread through food and water contaminated with feces containing bacteria. cholera bacteria.
Its typical symptom is profuse watery diarrhea, which can cause dehydration so severe that a person's skin turns bluish-gray and, in extreme cases, death within 24 hours. There is a possibility.
Risk factors for the disease include poor sanitation, insufficient clean drinking water, and poverty, which is rapidly increasing worldwide since 2021 and requires easy, effective and affordable treatment. Despite the law, the death rate remains high.
The WHO reported 473,000 infections in 2022, more than double the number from the previous year. From January 2023 to March 2024, a total of 824,479 cholera cases and 5,900 deaths were reported to WHO from 31 countries.
The surge in the epidemic is creating an unprecedented demand for vaccines from hard-hit countries including the Democratic Republic of the Congo, Ethiopia, Haiti, Somalia, Sudan, Syria, Zambia and Zimbabwe.
The world's supply of oral cholera vaccines increased 18-fold between 2013 and 2023, but the sudden, massive and sustained depletion of the global stockpile of cholera vaccines has led to depletion of stockpiles.
From 2021 to 2023, more vaccine doses were required to respond to outbreaks than in the entire past decade.
To deal with the emergency, the WHO's International Coordination Group on Vaccine Supply (ICG) has recommended switching from the long-standing two-dose regimen to one-dose vaccination.
However, this reduces immunity from about 4 to 6 months to 2 years.
Preventive vaccination campaigns have also been put on hold to secure doses for emergency outbreak control efforts, creating a vicious cycle.
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Sources 2/ https://www.telegraph.co.uk/global-health/science-and-disease/cholera-vaccine-global-demand-eubiologics-south-korea-seoul/ The mention sources can contact us to remove/changing this article |
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