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If bird flu causes a human pandemic, past immunity may be useful | The Transmission

If bird flu causes a human pandemic, past immunity may be useful | The Transmission

 


Nature Older people may be more protected than younger people because of exposure to “matching” strains during childhood, but an H5N1 pandemic would still likely take a greater toll.

As H5N1 avian influenza virus spreads relentlessly among animals In the worldThe researchers Human H5N1 pandemic For clues as to what will unfold, we have to rely on a rich source of data on the immune system's response. influenza.

Such information could shed light on who is most vulnerable to the H5N1 pandemic. Previous studies have shown that when confronted with the virus, our immune systems react by taking advantage of past infections and vaccination We have immunity to other types of influenza, but this immunity would not be enough to prevent H5N1 from causing serious damage to global health if a pandemic were to begin.

From feathers to fur

The currently raging H5N1 strain began as a bird pathogen The virus is classified as “highly pathogenic” because it is deadly to birds, and has killed millions of domestic and wild birds worldwide since it first emerged in 1996.1 It has also spread to mammals, including seals. and FoxSince 2003, it has caused more than 460 deaths.

So far, the virus has not acquired the ability to transmit efficiently from person to person, limiting pandemic potential, but there is evidence of repeated transmission from birds to mammals and between mammals, including elephant seals (Leonine Milunga)2Researchers are urging caution, warning that the virus is gaining an opportunity to spread more easily from person to person.

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2/ https://www.unmc.edu/healthsecurity/transmission/2024/07/10/if-bird-flu-sparks-a-human-pandemic-your-past-immunity-could-help/

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