October 12, 2024
2 minute read
October 12, 2024
2 minute read
In young adults without a history of arrhythmia, increased alcohol intake was associated with significantly increased heart rate and excessive atrial tachycardia, according to a study published in . european heart journal.
As Helio previously reportedresults from the MunichBREW study revealed a significant association between breath alcohol concentration and arrhythmia. But researchers say questions remain on the subject.
“Most data reporting alcohol-related arrhythmias come from small case series, secondary retrospective analyses, or heterogeneous study cohorts.” Dr. Stefan Brunner, Professors and colleagues at the Department of Medicine and Center for Sports Medicine at Ludwig-Maximilians-University Munich LMU University Hospital in Munich, Germany, wrote: “Also, the MunichBREW study had a cross-sectional design. Therefore, late-onset arrhythmias following acute excessive alcohol intake were missed.”
Investigate the time course during and after the onset of arrhythmias excessive alcohol intakeBrunner et al. were a prospective, physician-led, single-arm, single-center cohort study of 193 people (mean age 30 years, 36% female) with no history of cardiac arrhythmia who spontaneously planned for an acute phase. Conducted the MunichBREW II study. Alcohol consumption with an expected peak breath alcohol concentration (BAC) of at least 1.2 g/kg from October 2016 to July 2017.
Researchers used handheld breathalyzers to assess BAC at baseline and then hourly for up to eight hours.
Alcoholic beverages consumed by participants included beer (0.5L, ethanol 20g), wine (0.25L, ethanol 20g), Western liquor (0.02L, ethanol 6.2g), and long drinks (Western liquor 0.04L, 12.4g). It was. ethanol).
Starting at baseline (0 hours), participants wore a patch Holter monitor during the drinking period (1-5 hours), the recovery period (6-19 hours), and the control period 1 (25-29 hours). , and ECGs were recorded for 48 hours over control period 1 (25-29 hours). Control period 2 (30th to 43rd hour).
The researchers analyzed ECG findings for selected measures of mean heart rate, atrial tachycardia, premature atrial complexes, premature ventricular complexes, and heart rate variability.
During the drinking period, participants' average maximum BAC was 1.4 ± 0.4 g/kg, which was a similar level for men and women.
Brunner et al. observed a significant increase in heart rate (P < .001), concurrently with increased alcohol consumption excessive atrial tachycardia occurred, with a mean baseline heart rate of 89.5 ± 12.6 bpm compared to a maximum mean heart rate after 4 hours. The number reached 97 ± 16.2 bpm.
The researchers also found that premature atrial complexes were suppressed during the sobriety and recovery periods, but were significantly increased during control period 1 and control period 2.
Conversely, premature ventricular complexes occurred more frequently during the sobriety and recovery periods and less frequently during both control periods.
Additionally, the researchers found that 10 participants experienced significant arrhythmia episodes, primarily during recovery, including atrial fibrillation, brief arrhythmogenic atrial tachycardia, nonsustained ventricular tachycardia, and varying degrees of atrioventricular block. I pointed out what I had experienced.
“Our data support the understanding that alcohol-induced modulation of the autonomic nervous system is involved in the development of arrhythmias,” the researchers wrote. “To put it all together, “Holiday Heart Syndrome” Although it remains rare in otherwise healthy people, it should be recognized as a relevant health problem. ”
The researchers acknowledged some study limitations, including not being able to fully ascertain specific details about pre-existing arrhythmias or cardiovascular disorders because participants' medical histories were primarily based on self-reports. .
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